Literature identifier | Study type | Test dosage | Effective dosage | Endocrine-mediated endpoints | Systems-level perturbations |
---|---|---|---|---|---|
PMID:1288759 | IVR | 250 mg/kg/day | 250 mg/kg/day | Affects spermatogenesis | Reproductive endocrine-mediated perturbations |
PMID:4065311 | IVR | 250 mg/kg | 250 mg/kg | Affects spermatogenesis | Reproductive endocrine-mediated perturbations |
PMID:6499822 | IVR | 62.5 mg/kg | 62.5 mg/kg | Affects skeletal development in fetus | Developmental endocrine-mediated perturbations |
IVR | 62.5 mg/kg | 62.5 mg/kg | Affects skeletal development | Developmental endocrine-mediated perturbations | |
IVR | 250 mg/kg | 250 mg/kg | Affects skeletal development in fetus | Developmental endocrine-mediated perturbations | |
IVR | 250 mg/kg | 250 mg/kg | Testicular atrophy | Reproductive endocrine-mediated perturbations | |
IVR | 250 mg/kg | 250 mg/kg | Affects skeletal development | Developmental endocrine-mediated perturbations | |
IVR | 250 mg/kg | 250 mg/kg | Increased testis weights | Reproductive endocrine-mediated perturbations | |
IVR | 250 mg/kg | 250 mg/kg | Affects developmental process | Developmental endocrine-mediated perturbations | |
IVR | 1000 mg/kg | 1000 mg/kg | Affects survival of live fetus | Reproductive endocrine-mediated perturbations | |
IVR | 500 mg/kg | 500 mg/kg | Affects developmental process | Developmental endocrine-mediated perturbations | |
IVR | 500 mg/kg | 500 mg/kg | Affects skeletal development | Developmental endocrine-mediated perturbations | |
IVR | 500 mg/kg | 500 mg/kg | Affects skeletal development in fetus | Developmental endocrine-mediated perturbations | |
IVR | 500 mg/kg | 500 mg/kg | Increased testis weights | Reproductive endocrine-mediated perturbations | |
IVR | 500 mg/kg | 500 mg/kg | Changes in haemocrit values | Immunological endocrine-mediated perturbations | |
IVR | 500 mg/kg | 500 mg/kg | Testicular atrophy | Reproductive endocrine-mediated perturbations | |
IVR | 125 mg/kg | 125 mg/kg | Affects skeletal development in fetus | Developmental endocrine-mediated perturbations | |
IVR | 125 mg/kg | 125 mg/kg | Affects skeletal development | Developmental endocrine-mediated perturbations | |
IVR | 125 mg/kg | 125 mg/kg | Affects developmental process | Developmental endocrine-mediated perturbations | |
IVR | 125 mg/kg | 125 mg/kg | Increased testis weights | Reproductive endocrine-mediated perturbations | |
IVR | 125 mg/kg | 125 mg/kg | Testicular atrophy | Reproductive endocrine-mediated perturbations |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.