IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

Bioactivity information

Target name	Target organism	UniProt identifier	EC50	IC50	Kd	Ki	Source
Hepatitis C virus	Hepatitis C virus		= 20200.0 nM				NPASS
Prostaglandin G/H synthase 1	Bos taurus	O62664		170000 nM			BindingDB
NAD-dependent protein deacetylase sirtuin-6	Homo sapiens	Q8N6T7	= 100000.0 nM\|= 230000.0 nM				NPASS
NAD-dependent protein deacylase sirtuin-6	Homo sapiens	Q8N6T7	230000 nM\|100000 nM				BindingDB
Nuclear receptor subfamily 4 group A member 2	Homo sapiens	P43354			= 50000.0 nM		NPASS
Peroxisome proliferator-activated receptor alpha	Homo sapiens	Q07869		1100 nM\|= 1100.0 nM	4.8 nM\|= 4.8 nM		BindingDB, NPASS
Peroxisome proliferator-activated receptor delta	Homo sapiens	Q03181		10000 nM\|= 10000.0 nM			BindingDB, NPASS
Peroxisome proliferator-activated receptor gamma	Homo sapiens	P37231		6200 nM\|= 6200.0 nM			BindingDB, NPASS
Prostaglandin G/H synthase 1	Homo sapiens	P23219		13000 nM			BindingDB
Seed linoleate 13S-lipoxygenase-1	Glycine max	P08170		11000 nM\|13000 nM\|1000 nM			BindingDB
Protein-tyrosine phosphatase LC-PTP	Homo sapiens	P35236		> 100000.0 nM			NPASS
RBL-2H3	Rattus norvegicus			> 50000.0 nM			NPASS
SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2			> 20000.0 nM\|> 19952.62 nM			NPASS
Seed lipoxygenase-1	Glycine max	P08170		= 11000.0 nM\|= 13000.0 nM\|= 1000.0 nM			NPASS
Tyrosine-protein phosphatase non-receptor type 7	Homo sapiens	P35236		>100000 nM			BindingDB
Sterol O-acyltransferase 1	Rattus norvegicus	O70536		>1000000 nM			BindingDB
Tissue factor	Homo sapiens	P13726		41000 nM			BindingDB
Trypsin	Sus scrofa	P00761		>200000 nM\|> 200000.0 nM			BindingDB, NPASS
GPR40-Galpha16	Homo sapiens	O14842\|P30679	= 10100.0 nM				NPASS
Prostaglandin G/H synthase 2	Ovis aries	P79208		94000 nM			BindingDB
G-protein coupled receptor 120	Homo sapiens	Q5NUL3	= 316.23 nM				NPASS
Sterol O-acyltransferase 1	Homo sapiens	P35610		>1000000 nM			BindingDB
Free fatty acid receptor 1	Homo sapiens	O14842	540 nM\|1800 nM\|4800 nM\|= 540.0 nM\|= 549.54 nM\|= 1800.0 nM\|= 4800.0 nM\|= 6043.0 nM				BindingDB, NPASS
Free fatty acid receptor 4	Homo sapiens	Q5NUL3	316 nM				BindingDB
Acyl coenzyme A:cholesterol acyltransferase 1	Rattus norvegicus	O70536		> 1000000.0 nM			NPASS
Adenosine A1 receptor	Rattus norvegicus	P25099		= 65000.0 nM			NPASS
Adenosine receptor A1	Rattus norvegicus	P25099		65000 nM			BindingDB
Aldo-keto reductase family 1 member C3	Homo sapiens	P42330		690 nM			BindingDB
Aldo-keto-reductase family 1 member C3	Homo sapiens	P42330		= 690.0 nM			NPASS
Aromatase	Homo sapiens	P11511		48000 nM			BindingDB
Coagulation factor VII/tissue factor	Homo sapiens	P13726		= 41000.0 nM			NPASS
Cyclooxygenase-1	Bos taurus	O62664		= 170000.0 nM			NPASS
Cyclooxygenase-1	Homo sapiens	P23219		= 13000.0 nM			NPASS
Acyl coenzyme A:cholesterol acyltransferase 1	Homo sapiens	P35610		> 1000000.0 nM			NPASS
Cytochrome P450 19A1	Homo sapiens	P11511		= 48000.0 nM			NPASS
Cyclooxygenase-2	Ovis aries	P79208		= 94000.0 nM			NPASS
Fatty acid-binding protein, adipocyte	Homo sapiens	P15090		17700 nM\|13600 nM\|1000 nM		6800 nM	BindingDB
Fatty acid-binding protein 5 [M35A,L60A]	Human	Q01469				3.47e+3 nM	BindingDB
Fatty acid-binding protein 5 [K24A,R33A,K34A]	Human	Q01469				2.17e+3 nM	BindingDB
Fatty acid-binding protein, heart	Homo sapiens	P05413		1000 nM		9300 nM	BindingDB
Fatty acid binding protein muscle	Homo sapiens	P05413		= 1000.0 nM		= 9300.0 nM	NPASS
Fatty acid binding protein adipocyte	Homo sapiens	P15090		= 13600.0 nM\|= 1000.0 nM\|= 17700.0 nM		= 6800.0 nM	NPASS
Dual specificity protein phosphatase 3	Homo sapiens	P51452		>100000 nM\|> 100000.0 nM			BindingDB, NPASS
Fatty acid-binding protein 5	Human	Q01469				1.26e+3 nM	BindingDB

a curated database

IMPPAT Phytochemical information:
Linoleic acid

Bioactivity information

IMPPAT Phytochemical information: Linoleic acid

Bioactivity information

IMPPAT Phytochemical information:
Linoleic acid