IMPPAT Phytochemical information: 
Cholesterol
Cholesterol
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Oxysterol-binding protein 1Homo sapiensP22059= 173.0 nMNPASS
Oxysterol-binding protein 2Homo sapiensQ969R2= 68.0 nMNPASS
Oxysterol-binding protein 2HumanQ969R268 nMBindingDB
Oxysterol-binding protein 2 [1-181,275-916]HumanQ969R260 nMBindingDB
Oxysterols receptor LXR-alphaHomo sapiensQ13133BindingDB
P-glycoprotein 1Homo sapiensP08183= 8200.0 nMNPASS
SW480Homo sapiens> 20000.0 nMNPASS
Steroid C26-monooxygenaseMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)P9WPL43.4e+2 nMBindingDB
Steroid C26-monooxygenaseMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)P9WPP01.1e+2 nMBindingDB
TspO-like proteinFremyella diplosiphon (Cyanobacterium)1.749e+5 nM|201600 nMBindingDB
Nuclear receptor ROR-gammaHomo sapiensP5144920 nM|418 nM|= 20.0 nM|= 418.0 nMBindingDB, NPASS
VeroChlorocebus aethiops> 128.0 ug.mL-1NPASS
SMMC-7721Homo sapiens> 20000.0 nMNPASS
MCF7Homo sapiens> 50000.0 nM|> 20000.0 nMNPASS
A549Homo sapiens> 20000.0 nMNPASS
HeLaHomo sapiens> 50000.0 nMNPASS
Lanosterol 14-alpha demethylaseHomo sapiensQ16850>200000 nMBindingDB
ATP-dependent translocase ABCB1Homo sapiensP081838200 nMBindingDB
Androgen ReceptorRattus norvegicusP15207> 42657.95 nMNPASS
BJHomo sapiens> 50000.0 nMNPASS
CCRF-CEMHomo sapiens> 50000.0 nMNPASS
Cytochrome P450 51Homo sapiensQ16850> 200000.0 nMNPASS
Androgen receptorRattus norvegicusP15207>42657.95 nMBindingDB
DNA polymerase alpha subunitHomo sapiensP09884> 500000.0 nMNPASS
DNA polymerase betaRattus norvegicusP06766>500000 nM|> 500000.0 nMBindingDB, NPASS
DNA topoisomerase IIHomo sapiensQ02880> 500000.0 nMNPASS
HL-60Homo sapiens> 20000.0 nMNPASS
HT-29Homo sapiens> 50000.0 nMNPASS
DNA polymerase alpha catalytic subunitHomo sapiensP09884>500000 nMBindingDB