IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

Bioactivity information

Target name	Target organism	UniProt identifier	EC50	IC50	Ki	Source
Leishmania braziliensis	Leishmabraziliensis			= 342130.0 nM		NPASS
Leishmania amazonensis	Leishmaamazonensis			= 342130.0 nM		NPASS
Induced myeloid leukemia cell differentiation protein Mcl-1	Homo sapiens	Q07820		24380 nM\|= 24380.0 nM	4060 nM\|= 4060.0 nM	BindingDB, NPASS
Hepatitis C virus	Hepacivirus hominis		> 150000.0 nM			NPASS
HepG2	Homo sapiens			> 100000.0 nM		NPASS
Hep 3B2	Homo sapiens			> 100000.0 nM		NPASS
Dermatophagoides pteronyssinus	Dermatophagoides pteronyssinus		= 0.032 g/m2			NPASS
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	Trypanosoma cruzi	P22513		691830 nM\|= 691830.0 nM		BindingDB, NPASS
Glyceraldehyde-3-phosphate dehydrogenase liver	Homo sapiens	P04406		= 691830.97 nM		NPASS
Glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	P04406		691831 nM		BindingDB
Dihydroorotate dehydrogenase (fumarate)	Leishmamajor	Q4QEW7		= 642100.0 nM\|= 630957.34 nM		NPASS
Dihydroorotate dehydrogenase (fumarate)	Leishmamajor			630957 nM\|642100 nM		BindingDB
Leishmania donovani	Leishmadonovani			= 342130.0 nM		NPASS
HL-60	Homo sapiens			> 50000.0 nM		NPASS
MCF7	Homo sapiens			> 50000.0 nM		NPASS
U-937	Homo sapiens			> 2000000.0 nM\|> 400000.0 nM\|> 50000.0 nM		NPASS
Monoamine oxidase B	Rattus norvegicus	P19643		= 12022.64 nM		NPASS
Carbonic anhydrase XIV	Homo sapiens	Q9ULX7			= 48.0 nM\|> 200000.0 nM	NPASS
Zn finger protein	Nicotiana tabacum	Q43570			> 100.0 nM	NPASS
Zn finger protein	Nicotiana tabacum				>100 nM	BindingDB
V79	Cricetulus griseus			> 100000.0 nM		NPASS
UDP-glucuronosyltransferase 2B7	Human	P16662		>3.00e+5 nM		BindingDB
UDP-glucuronosyltransferase 2B10	Human	P36537		>3.00e+5 nM		BindingDB
Monoamine oxidase A	Rattus norvegicus	P21396		= 40738.03 nM		NPASS
UDP-glucuronosyltransferase 1A4	Human	P22310		>3.00e+5 nM		BindingDB
UDP-glucuronosyltransferase 1-6	Human	P19224		>3.00e+5 nM		BindingDB
Sorbitol dehydrogenase	Homo sapiens	Q00796		>400000 nM\|> 400000.0 nM		BindingDB, NPASS
SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2			> 20000.0 nM\|> 19952.62 nM		NPASS
OVCAR-3	Homo sapiens			> 100000.0 nM		NPASS
NON-PROTEIN TARGET				> 50000.0 nM		NPASS
NAD-dependent histone deacetylase SIR2	Saccharomyces cerevisiae S288c	P06700		>= 150000.0 nM		NPASS
UDP-glucuronosyltransferase 1A1	Human	P22309		>3.00e+5 nM		BindingDB
Carbonic anhydrase XIII	Mus musculus	Q9D6N1			= 9200.0 nM	NPASS
Exportin-1	Homo sapiens	O14980		>25000 nM\|> 25000.0 nM		BindingDB, NPASS
Carbonic anhydrase XII	Homo sapiens	O43570			= 8900.0 nM\|> 500000.0 nM\|> 200000.0 nM\|> 100000.0 nM\|> 1000000.0 nM	NPASS
A2780	Homo sapiens			> 100000.0 nM		NPASS
Acetylcholinesterase	Mus musculus	P21836			9300 nM	BindingDB
Aldo-keto reductase family 1 member B1	Homo sapiens	P15121		>500000 nM		BindingDB
Aldose reductase	Homo sapiens	P15121		> 500000.0 nM		NPASS
Amine oxidase [flavin-containing] A	Rattus norvegicus	P21396		40738.03 nM		BindingDB
Amine oxidase [flavin-containing] B	Rattus norvegicus	P19643		12022.64 nM		BindingDB
Beta-secretase 1	Homo sapiens	P56817		>500000 nM\|> 500000.0 nM		BindingDB, NPASS
Bile salt export pump	Homo sapiens	O95342		>1000000 nM\|> 1000000.0 nM		BindingDB, NPASS
Carbonic anhydrase 1	Homo sapiens	P00915			3100 nM	BindingDB
Carbonic anhydrase 12	Homo sapiens	O43570			>100000 nM\|>500000 nM\|>200000 nM\|8900 nM\|>1000000 nM	BindingDB
Carbonic anhydrase 13	Homo sapiens	Q8N1Q1			>200000 nM\|>1000000 nM	BindingDB
Carbonic anhydrase 13	Mus musculus	Q9D6N1			9200 nM	BindingDB
Carbonic anhydrase 14	Homo sapiens	Q9ULX7			>200000 nM\|48 nM	BindingDB
Carbonic anhydrase XIII	Homo sapiens	Q8N1Q1			> 200000.0 nM\|> 1000000.0 nM	NPASS
Carbonic anhydrase 2	Homo sapiens	P00918			9200 nM\|>500000 nM	BindingDB
Carbonic anhydrase 15	Mus musculus	Q99N23			39600 nM\|= 39600.0 nM	BindingDB, NPASS
Carbonic anhydrase 4	Homo sapiens	P22748			62300 nM\|6800 nM	BindingDB
Carbonic anhydrase VII	Homo sapiens	P43166			= 3300.0 nM\|> 200000.0 nM\|> 1000000.0 nM	NPASS
Carbonic anhydrase VI	Homo sapiens	P23280			= 2000.0 nM\|> 200000.0 nM	NPASS
Carbonic anhydrase VB	Homo sapiens	Q9Y2D0			= 5200.0 nM\|> 200000.0 nM	NPASS
Carbonic anhydrase VA	Homo sapiens	P35218			= 9400.0 nM\|> 200000.0 nM	NPASS
Carbonic anhydrase IX	Homo sapiens	Q16790			= 9100.0 nM\|> 100.0 nM\|> 100000.0 nM\|> 500000.0 nM\|> 200000.0 nM\|> 1000000.0 nM	NPASS
Carbonic anhydrase 3	Homo sapiens	P07451			>200000 nM\|5600 nM	BindingDB
Carbonic anhydrase III	Homo sapiens	P07451			= 5600.0 nM\|> 200000.0 nM	NPASS
Carbonic anhydrase IV	Homo sapiens	P22748			= 6800.0 nM\|= 62300.0 nM	NPASS
Carbonic anhydrase I	Homo sapiens	P00915			= 3100.0 nM	NPASS
Carbonic anhydrase 9	Homo sapiens	Q16790			>100000 nM\|>100 nM\|>500000 nM\|>200000 nM\|9100 nM\|>1000000 nM	BindingDB
Carbonic anhydrase 7	Homo sapiens	P43166			>200000 nM\|3300 nM\|>1000000 nM	BindingDB
Carbonic anhydrase 6	Homo sapiens	P23280			>200000 nM\|2000 nM	BindingDB
Carbonic anhydrase 5B, mitochondrial	Homo sapiens	Q9Y2D0			>200000 nM\|5200 nM	BindingDB
Carbonic anhydrase 5A, mitochondrial	Homo sapiens	P35218			>200000 nM\|9400 nM	BindingDB
Carbonic anhydrase II	Homo sapiens	P00918			> 500000.0 nM\|= 9200.0 nM	NPASS

a curated database

IMPPAT Phytochemical information:
Coumarin

Bioactivity information

IMPPAT Phytochemical information: Coumarin

Bioactivity information

IMPPAT Phytochemical information:
Coumarin