IMPPAT Phytochemical information: 
Osthole
Osthole
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Leishmania majorLeishmamajor= 14.95 ug.mL-1NPASS
MCF7Homo sapiens= 25800.0 nMNPASS
MDA-MB-231Homo sapiens= 30200.0 nMNPASS
MM46Mus musculus= 8.6 ug.mL-1NPASS
NON-PROTEIN TARGET= 30200.0 nM|= 30900.0 nM|= 24800.0 nMNPASS
SH-SY5YHomo sapiens= 33260.0 nM|= 26450.0 nMNPASS
P388Mus musculus= 3.1 ug.mL-1NPASS
RAW264.7Mus musculus= 12400.0 nMNPASS
Rhizoctonia solaniRhizoctosolani= 6.88 ug.mL-1NPASS
KBHomo sapiens= 12.0 ug.mL-1NPASS
T47DHomo sapiens= 42400.0 nMNPASS
V79Cricetulus griseus= 57000.0 nMNPASS
P-glycoprotein 1Homo sapiensP08183= 34000.0 nMNPASS
HepG2Homo sapiens= 161400.0 nMNPASS
Exportin-1Homo sapiensO14980= 1600.0 nMNPASS
GABA-A receptor; alpha-1/beta-2/gamma-2Homo sapiensP18507= 14000.0 nMNPASS
A-431Homo sapiens= 23200.0 nMNPASS
A10Rattus norvegicus= 13600.0 nMNPASS
Glyceraldehyde-3-phosphate dehydrogenase liverHomo sapiensP04406= 208929.61 nMNPASS
Arachidonate 5-lipoxygenaseHomo sapiensP09917= 36200.0 nMNPASS
Beta-secretase 1Homo sapiensP56817> 500000.0 nMNPASS
A549Homo sapiens= 46200.0 nMNPASS
COLO 205Homo sapiens> 60000.0 nMNPASS
Colletotrichum camelliaeColletotrichum camelliae= 16.83 ug.mL-1NPASS
Cyclooxygenase-1Homo sapiensP23219> 200000.0 nMNPASS
Cyclooxygenase-1Ovis ariesP05979= 52500.0 nMNPASS
Cyclooxygenase-2Homo sapiensP35354= 81100.0 nMNPASS
Botrytis cinereaBotrytis cinerea= 6.45 ug.mL-1NPASS