IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

Bioactivity information

Target name	Target organism	UniProt identifier	EC50	IC50	Kd	Ki	Source
Alpha-2b adrenergic receptor	Homo sapiens	P18089	= 61.66 nM				NPASS
Alpha-2b adrenergic receptor	Rattus norvegicus	P19328				= 78.0 nM	NPASS
Alpha-2c adrenergic receptor	Homo sapiens	P18825	= 794.33 nM			= 63.0 nM	NPASS
Beta-1 adrenergic receptor	Cavia porcellus		10000 nM\|30 nM\|350 nM			400 nM	BindingDB
Beta-1 adrenergic receptor	Cavia porcellus	B0FL73	= 10000.0 nM\|= 30.0 nM\|= 350.0 nM			= 400.0 nM	NPASS
Beta-2 adrenergic receptor	Rattus norvegicus	P10608				4200 nM\|= 4200.0 nM	BindingDB, NPASS
Beta-1/Beta-2/Beta-3 adrenergic receptor	Homo sapiens	P07550\|P08588\|P13945	2600 nM				BindingDB
Beta-1/Beta-2/Beta-3 adrenergic receptor	Rattus norvegicus	P10608\|P18090\|P26255	52 nM	1000 nM			BindingDB
Beta-2 adrenergic receptor	Bos taurus	Q28044				6000 nM\|= 6000.0 nM	BindingDB, NPASS
Beta-2 adrenergic receptor	Canis lupus familiaris	P54833				11000 nM\|= 11000.0 nM\|= 27000.0 nM\|= 5000.0 nM	BindingDB, NPASS
Beta-2 adrenergic receptor	Cavia porcellus	Q8K4Z4	213 nM\|= 30000.0 nM\|= 213.0 nM				BindingDB, NPASS
Beta-2 adrenergic receptor	Homo sapiens	P07550			3980 nM\|3981 nM\|= 3980.0 nM\|= 3981.07 nM	96700 nM\|3300 nM\|= 96700.0 nM\|= 217000.0 nM\|= 191000.0 nM\|= 134000.0 nM\|= 378000.0 nM\|= 1776000.0 nM\|= 342000.0 nM\|= 490000.0 nM\|= 3300.0 nM	BindingDB, NPASS
Beta-1 adrenergic receptor	Rattus norvegicus	P18090				2700 nM\|126 nM\|1600 nM\|= 126.0 nM\|= 2700.0 nM\|= 26000.0 nM\|= 1300.0 nM\|= 1600.0 nM	BindingDB, NPASS
Bile salt export pump	Homo sapiens	O95342		>1000000 nM\|> 1000000.0 nM			BindingDB, NPASS
Cavia porcellus	Cavia porcellus		= 1500.0 nM				NPASS
D(1A) dopamine receptor	Homo sapiens	P21728			50000 nM		BindingDB
D(2) dopamine receptor	Homo sapiens	P14416		0.000 nM		1300 nM	BindingDB
D-amino-acid oxidase	Homo sapiens	P14920		>10000000 nM\|> 10000000.0 nM			BindingDB, NPASS
Dopamine D1 receptor	Homo sapiens	P21728			= 50000.0 nM		NPASS
Dopamine D2 receptor	Homo sapiens	P14416		= 8e-05 nM		= 1300.0 nM	NPASS
Mu-type opioid receptor	Rattus norvegicus	P33535				14000 nM	BindingDB
Nischarin	Homo sapiens	Q9Y2I1				>100000 nM\|> 100000.0 nM	BindingDB, NPASS
SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2			> 20000.0 nM\|> 19952.62 nM			NPASS
Solute carrier family 22 member 2	Rattus norvegicus	Q9R0W2		11000000 nM\|= 11000000.0 nM			BindingDB, NPASS
Solute carrier family 22 member 3	Rattus norvegicus	O88446		434000 nM\|= 434000.0 nM			BindingDB, NPASS
Vesicular acetylcholine transporter	Rattus norvegicus	Q62666				>10000 nM\|> 10000.0 nM	BindingDB, NPASS
Alpha-2a adrenergic receptor	Homo sapiens	P08913	= 371.54 nM\|= 110.0 nM\|= 118.0 nM\|= 128.82 nM			= 66.0 nM	NPASS
Beta-3 adrenergic receptor	Homo sapiens	P13945	6.3 nM\|5.5 nM\|= 5.5 nM\|= 6.3 nM				BindingDB, NPASS
Alpha-2C adrenergic receptor	Homo sapiens	P18825	794 nM			63 nM	BindingDB
Beta-3 adrenergic receptor	Rattus norvegicus	P26255	1580 nM\|100000 nM\|= 100000.0 nM\|= 1580.0 nM				BindingDB, NPASS
Alpha-2B adrenergic receptor	Homo sapiens	P18089	62 nM				BindingDB
3T3-L1	Mus musculus			= 69.0 ug.mL-1\|> 100.0 ug.mL-1			NPASS
Adrenergic receptor alpha	Rattus norvegicus	P22909		= 16.0 nM\|= 5000.0 nM			NPASS
Adrenergic receptor alpha-1	Homo sapiens	P35368				= 2600.0 nM	NPASS
Adrenergic receptor alpha-1	Rattus norvegicus	P43140	= 83200.0 nM\|= 200.0 nM\|= 15800.0 nM\|= 1.2 nM	= 1500.0 nM\|= 1620.0 nM		= 390.0 nM\|= 450.0 nM\|= 6500.0 nM\|= 3000.0 nM\|= 1000.0 nM\|= 500.0 nM\|= 4000.0 nM	NPASS
Adrenergic receptor alpha-2	Homo sapiens	P18089	= 166.0 nM			= 30.0 nM	NPASS
Adrenergic receptor alpha-2	Rattus norvegicus	P22909		= 750.0 nM\|= 33.0 nM		= 37.0 nM\|= 17.0 nM\|= 4.8 nM\|= 30.0 nM\|= 340.0 nM\|= 20.0 nM\|= 38.0 nM	NPASS
Adrenergic receptor beta	Homo sapiens	P13945	= 2600.0 nM				NPASS
Adrenergic receptor beta	Rattus norvegicus	P26255	= 52.0 nM	= 1000.0 nM			NPASS
Alpha-1A adrenergic receptor	Bos taurus	P18130				447 nM	BindingDB
Alpha-1A adrenergic receptor	Homo sapiens	P35348	9.1 nM\|2188 nM			1500 nM	BindingDB
Alpha-1A adrenergic receptor	Rattus norvegicus	P43140	1175 nM			282 nM	BindingDB
Alpha-1A adrenergic receptor/Alpha-1B adrenergic receptor/Alpha-1D adrenergic receptor/Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor	Rattus norvegicus	P15823\|P19328\|P22086\|P22909\|P23944\|P43140		16 nM\|5000 nM			BindingDB
Alpha-2B adrenergic receptor	Rattus norvegicus	P19328				78 nM	BindingDB
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor	Rattus norvegicus	P15823\|P23944\|P43140		1620 nM		500 nM\|390 nM\|450 nM\|1000 nM	BindingDB
Alpha-1B adrenergic receptor	Homo sapiens	P35368				20400 nM	BindingDB
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor	Homo sapiens	P08913\|P18089\|P18825				30 nM	BindingDB
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor	Rattus norvegicus	P19328\|P22086\|P22909		33 nM		17 nM\|37 nM\|4.8 nM\|38 nM	BindingDB
Alpha-2A adrenergic receptor	Homo sapiens	P08913	372 nM\|110 nM\|118 nM\|129 nM			4100 nM\|66 nM	BindingDB
Alpha-1d adrenergic receptor	Rattus norvegicus	P23944	= 12.02 nM			= 22.39 nM	NPASS
Alpha-1b adrenergic receptor	Rattus norvegicus	P15823	= 10232.93 nM				NPASS
Alpha-1B adrenergic receptor	Cricetidae sp.	P18841				263 nM	BindingDB
Alpha-1b adrenergic receptor	Mesocricetus auratus	P18841				= 263.03 nM	NPASS
Alpha-1a adrenergic receptor	Rattus norvegicus	P43140	= 1174.9 nM			= 281.84 nM	NPASS
Alpha-1a adrenergic receptor	Homo sapiens	P35348	= 2187.76 nM\|= 9.1 nM			= 1500.0 nM	NPASS
Alpha-1a adrenergic receptor	Bos taurus	P18130				= 446.68 nM	NPASS
Alpha-1D adrenergic receptor	Rattus norvegicus	P23944	12 nM			22 nM	BindingDB
Alpha-1B adrenergic receptor	Rattus norvegicus	P15823	10233 nM				BindingDB
Alpha-1b adrenergic receptor	Homo sapiens	P35368				= 20400.0 nM	NPASS

a curated database

IMPPAT Phytochemical information:
Norepinephrine

Bioactivity information

IMPPAT Phytochemical information: Norepinephrine

Bioactivity information

IMPPAT Phytochemical information:
Norepinephrine