| Target name | Target organism | UniProt identifier | EC50 | IC50 | Kd | Ki | Source |
|---|
| Neuronal acetylcholine receptor; alpha2/beta2 | Rattus norvegicus | P12390 | | | | = 11.0 nM | NPASS |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus | Q05941 | 127600 nM|208930 nM|205300 nM|3120 nM|110000 nM | | | >10000 nM|170000 nM | BindingDB |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens | P36544 | 87000 nM|69000 nM|230000 nM|155000 nM|180000 nM|4000 nM|83000 nM | | | 7943.28 nM|501 nM | BindingDB |
| Neuronal acetylcholine receptor subunit alpha-4/beta-4 | Rattus norvegicus | P09483|P12392 | 19000 nM | | | 83 nM | BindingDB |
| Neuronal acetylcholine receptor subunit alpha-4/beta-2 | Homo sapiens | P17787|P43681 | 400 nM|100000 nM|1000 nM|1600 nM | | | | BindingDB |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus | P09483 | | | | 33 nM|58 nM|44 nM|99 nM|39 nM | BindingDB |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens | P43681 | 70000 nM | | | 2.66 nM|6.8 nM|>10000 nM | BindingDB |
| Neuronal acetylcholine receptor; alpha3/beta2 | Homo sapiens | P32297 | = 443000.0 nM | | | | NPASS |
| Neuronal acetylcholine receptor subunit alpha-3/beta-4 | Homo sapiens | P30926|P32297 | 30000 nM | | | | BindingDB |
| Neuronal acetylcholine receptor subunit alpha-3/beta-4 | Rattus norvegicus | P04757|P12392 | 217000 nM | | | 820 nM|881 nM | BindingDB |
| Neuronal acetylcholine receptor subunit alpha-4/beta-2 | Rattus norvegicus | P09483|P12390 | 270000 nM|87000 nM|24000 nM | | | 45 nM|7.6 nM | BindingDB |
| Neuronal acetylcholine receptor; alpha3/beta2 | Rattus norvegicus | P12390 | | | | = 41.0 nM | NPASS |
| Neuropeptide Y receptor type 2 | Homo sapiens | P49146 | | >35000 nM | | | BindingDB |
| Neuronal acetylcholine receptor; alpha3/beta4 | Rattus norvegicus | P12392 | = 217000.0 nM|= 8700.0 nM|= 7943.28 nM|= 8900.0 nM | | | = 820.0 nM|= 881.0 nM|= 620.0 nM|= 616.6 nM | NPASS |
| Neuronal acetylcholine receptor; alpha4/beta2 | Homo sapiens | P43681 | = 70000.0 nM|= 70794.58 nM|= 1000.0 nM|= 100000.0 nM|= 1600.0 nM|= 73.0 nM|= 1.7 nM|= 400.0 nM | | | | NPASS |
| Neuronal acetylcholine receptor; alpha4/beta2 | Rattus norvegicus | P12390 | = 270000.0 nM|= 87000.0 nM|= 24000.0 nM | | | = 45.0 nM|= 7.6 nM|= 39.0 nM|= 37.7 nM|= 33.11 nM|= 33.0 nM | NPASS |
| Neuronal acetylcholine receptor; alpha4/beta4 | Rattus norvegicus | P12392 | = 19000.0 nM | | | = 83.0 nM|= 57.54 nM|= 58.0 nM | NPASS |
| Neuropeptide Y receptor type 1 | Homo sapiens | P25929 | | >35000 nM | | | BindingDB |
| Nicotinic acetylcholine receptor | Rattus leucopus | | | | | 47.3 nM|32.8 nM|4 nM|45 nM | BindingDB |
| Nicotinic acetylcholine receptor alpha8 subunit | Periplaneta americana | H6TY12 | = 11481.54 nM | | | | NPASS |
| Resistance to inhibitors of cholinesterase protein 3 | Pig roundworm | F1L1D9 | 6360 nM | | | | BindingDB |
| SARS-CoV-2 | Severe acute respiratory syndrome coronavirus 2 | | | > 20000.0 nM|> 19952.62 nM | | | NPASS |
| Tropomyosin alpha-1 chain | Sus scrofa | P42639 | >71402 nM | | | | BindingDB |
| Neuronal acetylcholine receptor subunit alpha-3/beta-2 | Rattus norvegicus | P04757|P12390 | | | | 41 nM | BindingDB |
| Neuronal acetylcholine receptor; alpha3/beta4 | Homo sapiens | P32297 | = 30000.0 nM|= 19000.0 nM|= 19952.62 nM|= 144000.0 nM|= 144543.98 nM|= 127000.0 nM | | | | NPASS |
| Neuronal acetylcholine receptor subunit alpha-3/beta-2 | Homo sapiens | P17787|P32297 | 443000 nM | | | | BindingDB |
| Cholinergic receptor nicotinic alpha 6 subunit | Gallus gallus | | | | | 123 nM | BindingDB |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens | P32297 | 19000 nM|144000 nM | | | | BindingDB |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus | P04757 | 8900 nM | | | 881 nM|620 nM|56 nM|850 nM | BindingDB |
| Acetylcholine receptor protein delta chain | Torpedo californica | P02718 | = 5000.0 nM | | | | NPASS |
| Acetylcholine receptor subunit delta | Tetronarce californica | P02718 | 40000 nM | | | | BindingDB |
| Acetylcholine-binding protein | Lymnaea stagnalis | P58154 | | | 458 nM|3850 nM | 3162.28 nM|6309.57 nM|= 3162.28 nM|= 6309.57 nM | BindingDB, NPASS |
| Beta-arrestin-1 | Oryctolagus cuniculus | Q95223 | | | | 3230 nM | BindingDB |
| Bile salt export pump | Homo sapiens | O95342 | | >1000000 nM|> 1000000.0 nM | | | BindingDB, NPASS |
| Cannabinoid receptor 1 | Hirudo medicinalis | | | | | 1000 nM | BindingDB |
| G protein-activated inward rectifier potassium channel 1 | Rattus norvegicus | P63251 | 0.06142 nM | | | | BindingDB |
| Galanin receptor type 3 | Homo sapiens | O60755 | | 1658 nM|617.81 nM | | | BindingDB |
| Muscarinic acetylcholine receptor | Rattus norvegicus | P10980 | | = 12.0 nM|= 24000.0 nM | | = 85.0 nM | NPASS |
| Muscarinic acetylcholine receptor M1 | Homo sapiens | P11229 | 20000 nM|100000 nM|372 nM|26 nM|770 nM|617 nM|620 nM|47 nM|1.1 nM|= 20000.0 nM|= 27000.0 nM|= 1.1 nM|= 100000.0 nM|= 371.54 nM|= 25.9 nM|= 616.6 nM|= 620.0 nM|= 46.77 nM|= 47.0 nM|= 190.55 nM | 135 nM|= 134.9 nM | 17378 nM|= 17378.01 nM | 3.4 nM|13490 nM|12589 nM|23000 nM|5800 nM|22909 nM|= 13489.63 nM|= 12589.25 nM|= 5800.0 nM|= 22908.68 nM|= 23000.0 nM | BindingDB, NPASS |
| Aorta | Rattus norvegicus | | | = 1000.0 nM | | | NPASS |
| Muscarinic acetylcholine receptor M2 | Homo sapiens | P08172 | 7.0 nM|513 nM|510 nM|49 nM|1905 nM|1900 nM|13 nM|56 nM|220 nM|= 220.0 nM|= 7.0 nM|= 56.0 nM|= 512.86 nM|= 510.0 nM|= 48.98 nM|= 49.0 nM|= 1905.46 nM|= 1900.0 nM|= 12.59 nM|= 13.0 nM|= 165.96 nM | | | 347 nM|340 nM|158 nM|380 nM|390 nM|= 158.49 nM|= 390.0 nM|= 380.19 nM|= 380.0 nM | BindingDB, NPASS |
| Neuronal acetylcholine receptor subunit alpha-2/beta-2 | Rattus norvegicus | P12389|P12390 | | | | 11 nM | BindingDB |
| Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 | Rattus norvegicus | P08482|P08483|P08485|P08911|P10980 | | 24000 nM|12 nM | | | BindingDB |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus | P12389 | | | | 4.2 nM|110 nM|11 nM | BindingDB |
| Neuronal acetylcholine receptor protein alpha-7 subunit | Homo sapiens | P36544 | = 155000.0 nM|= 230000.0 nM|= 180000.0 nM|= 4000.0 nM|= 3981.07 nM|= 83000.0 nM|= 83176.38 nM|= 87000.0 nM|= 69000.0 nM | | | = 7943.28 nM|= 501.19 nM | NPASS |
| Neuronal acetylcholine receptor | Rattus norvegicus | Q05941 | = 40000.0 nM | | | = 43.0 nM | NPASS |
| Neuronal acetylcholine receptor protein alpha-7 subunit | Rattus norvegicus | Q05941 | = 3120.0 nM|= 127600.0 nM|= 208929.61 nM|= 205300.0 nM|= 110000.0 nM | | | = 3509.0 nM|= 169824.37 nM|= 170000.0 nM|= 25000.0 nM | NPASS |
| Muscarinic acetylcholine receptor M4 | Homo sapiens | P08173 | 49 nM|10 nM|57 nM|43 nM|= 10.0 nM|= 48.8 nM|= 43.0 nM|= 57.0 nM|= 134.9 nM | | | 5400 nM|8511 nM|= 8511.38 nM | BindingDB, NPASS |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus | P08483 | | | | 2400 nM | BindingDB |
| Muscarinic acetylcholine receptor M3 | Homo sapiens | P20309 | 205 nM|220 nM|240 nM|23 nM|3.2 nM|= 3.2 nM|= 205.0 nM|= 239.88 nM|= 240.0 nM|= 22.91 nM|= 23.0 nM|= 501.19 nM | | | 4200 nM|7079 nM|4700 nM|6761 nM|6800 nM|= 7079.46 nM|= 4700.0 nM|= 6760.83 nM|= 6800.0 nM | BindingDB, NPASS |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus | P10980 | | | | 700 nM|>10000 nM|2000 nM|430 nM | BindingDB |
| Muscarinic acetylcholine receptor M5 | Homo sapiens | P08912 | 630 nM|19 nM|790 nM|1.2 nM|= 630.0 nM|= 1.2 nM|= 19.1 nM|= 147.91 nM | | | 800 nM|9772 nM|= 9772.37 nM | BindingDB, NPASS |
