IMPPAT Phytochemical information: 
Lupenone
Lupenone
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Trypanosoma brucei rhodesienseTrypanosoma brucei rhodesiense> 90000.0 nMNPASS
SiHaHomo sapiens> 500000.0 nMNPASS
Reverse transcriptaseHuman immunodeficiency virus 14940 nMBindingDB
RAW264.7Mus musculus> 400.0 nM|= 38500.0 nMNPASS
Plasmodium falciparum (isolate K1 / Thailand)Plasmodium falciparum K1= 4700.0 nMNPASS
NON-PROTEIN TARGET= 77000.0 nM= 38800.0 nMNPASS
MDA-MB-231Homo sapiens> 500000.0 nMNPASS
VeroChlorocebus aethiops> 10.0 ug.mL-1|> 500000.0 nMNPASS
MCF7Homo sapiens> 500000.0 nMNPASS
Human immunodeficiency virus type 1 reverse transcriptaseHuman immunodeficiency virus 1Q72547= 2.1 ug.mL-1NPASS
KBHomo sapiens> 500000.0 nMNPASS
HeLaHomo sapiens> 10.0 ug.mL-1|> 500000.0 nMNPASS
HEp-2Homo sapiens> 10.0 ug.mL-1|> 500000.0 nMNPASS
HEK293Homo sapiens> 500000.0 nMNPASS
G-protein coupled bile acid receptor 1Homo sapiensQ8TDU6>10000 nM|> 10000.0 nMBindingDB, NPASS
DU-145Homo sapiens> 500000.0 nMNPASS
Bile acid receptor FXRHomo sapiensQ96RI1= 0.0 nMNPASS
B16Mus musculus= 25400.0 nMNPASS
L6Rattus norvegicus> 90000.0 nMNPASS