IMPPAT Phytochemical information: 
Adenosine
Adenosine
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Luciferin 4-monooxygenasePhotinus pyralisP08659> 112219.0 nMNPASS
L1210Mus musculus= 1869000.0 nM= 991000.0 nMNPASS
Inosine-5'-monophosphate dehydrogenase 2Homo sapiensP12268>100000 nM|> 100000.0 nMBindingDB, NPASS
Inosine-5'-monophosphate dehydrogenase 1Homo sapiensP20839>100000 nM|> 100000.0 nMBindingDB, NPASS
Homo sapiensHomo sapiens= 6000.0 nM|> 100000.0 nM|= 5940.0 nMNPASS
Histone-lysine N-methyltransferase, H3 lysine-79 specificHomo sapiensQ8TEK3100000 nM|= 100000.0 nMBindingDB, NPASS
HepG2Homo sapiens= 18460.0 nMNPASS
Glyceraldehyde-3-phosphate dehydrogenaseHomo sapiensP0440650000 nM|35000 nM|100000000 nM|35000000 nM|100000 nM|50000000 nM2500000 nMBindingDB
Heat shock cognate 71 kDa proteinHomo sapiensP11142112202 nM|110000 nM|= 112201.85 nM|= 110000.0 nMBindingDB, NPASS
Heat shock 70 kDa protein 1AHomo sapiensP0DMV8560000 nMBindingDB
HeLaHomo sapiens= 10800.0 nM|= 98850.0 nMNPASS
HEp-2Homo sapiens= 700.0 nM|= 20000.0 nMNPASS
Glycogen synthase kinase-3 betaHomo sapiensP49841>300000 nMBindingDB
Glyceraldehyde-3-phosphate dehydrogenase liverHomo sapiensP04406= 50000000.0 nM|= 100000.0 nM|= 50000.0 nM|= 35000.0 nM|= 100000000.0 nM|= 35000000.0 nM= 2500000.0 nMNPASS
METTL3/METTL14Homo sapiensQ86U44|Q9HCE5= 495000.0 nMNPASS
Heat shock protein HSP 90-alphaHomo sapiensP07900>50000 nM|> 50000.0 nM>3000 nM|> 3000.0 nMBindingDB, NPASS
Mitogen-activated protein kinase kinase kinase 7Homo sapiensO433184400 nM|34000 nM|= 4400.0 nM|= 34000.0 nMBindingDB, NPASS
Purine nucleoside phosphorylaseHomo sapiensP004912000000 nM|= 2000000.0 nMBindingDB, NPASS
PBMCHomo sapiens= 1867000.0 nMNPASS
cAMP-dependent protein kinase ABos taurusP00515= 160000.0 nM|= 1100000.0 nM= 15000.0 nMNPASS
Transmembrane and immunoglobulin domain-containing 3Rattus norvegicus>10000 nMBindingDB
StreptavidinStreptomyces avidiniiP22629168000 nM|= 168000.0 nMBindingDB, NPASS
Solute carrier family 28 member 3Homo sapiensQ9HAS33300 nM|= 3300.0 nM2100 nM|= 2100.0 nMBindingDB, NPASS
Sodium/nucleoside cotransporter 2Homo sapiensO438685500 nM|= 5500.0 nM5300 nM|= 5300.0 nMBindingDB, NPASS
Sodium/nucleoside cotransporter 1Homo sapiensO003375500 nM|= 5500.0 nM1800 nM|= 1800.0 nMBindingDB, NPASS
SARS-CoV-2Severe acute respiratory syndrome coronavirus 2> 20000.0 nM|> 19952.62 nMNPASS
N6-adenosine-methyltransferase catalytic subunitHomo sapiensQ86U44= 495000.0 nMNPASS
Receptor protein-tyrosine kinase erbB-2Homo sapiensP04626~ 1600000.0 nMNPASS
Genome polyproteinWest Nile virusP06935>50000 nMBindingDB
Protein kinase C beta typeHomo sapiensP05771278000 nMBindingDB
Protein kinase C betaHomo sapiensP05771= 278000.0 nMNPASS
Phosphoglycerate kinase 1Homo sapiensP005583000000 nMBindingDB
Phosphoglycerate kinaseHomo sapiensP07205= 3000000.0 nMNPASS
Phosphatidylinositol 4-kinase, PI4KHomo sapiensP42356= 30300.0 nM= 19200.0 nMNPASS
Phosphatidylinositol 4-kinase type 2-alphaHomo sapiensQ9BTU630300 nM19200 nMBindingDB
RAW264.7Mus musculus> 10000.0 nMNPASS
Equilibrative nucleoside transporter 2Homo sapiensQ14542106000 nM|= 106000.0 nM106000 nM|= 106000.0 nMBindingDB, NPASS
Rattus norvegicusRattus norvegicus= 26000.0 nMNPASS
Epidermal growth factor receptor erbB1Homo sapiensP00533= 195000.0 nMNPASS
Adenosine receptor A2aHomo sapiensP29274700 nM|730 nM|5754 nM|40000 nM|25 nM17 nM20 nM|700 nM|150 nMBindingDB
Adenosine receptor A1Rattus norvegicusP250991950 nM364 nM|>10000 nM|13 nM|5.1 nM|10 nM|29000 nM|871 nMBindingDB
Adenosine receptor A1Homo sapiensP30542310 nM|2512 nM|1410 nM|39 nM|69 nM2.3 nM295 nM813 nMBindingDB
Adenosine receptor A1Cavia porcellusP477453388 nM|3.388E3 nMBindingDB
Adenosine kinaseToxoplasma gondiiQ9TVW28900 nM|= 8900.0 nMBindingDB, NPASS
Adenosine deaminaseHomo sapiensP008132180000 nM|= 2180000.0 nMBindingDB, NPASS
Adenosine A3 receptorRattus norvegicusP28647= 100.0 nMNPASS
Adenosine receptor A2aRattus norvegicusP305434550 nM|>10000 nM|30 nMBindingDB
Adenosine A3 receptorHomo sapiensP0DMS8= 1040.0 nM|= 290.0 nM|= 13.49 nM= 1.148 nM= 740.0 nM= 290.0 nMNPASS
Adenosine A2a receptorRattus norvegicusP30543= 30.0 nMNPASS
Adenosine A2a receptorHomo sapiensP29274= 40000.0 nM|= 700.0 nM|= 5754.4 nM|= 730.0 nM|= 25.12 nM= 17.3 nM= 20.0 nM|= 700.0 nM|= 150.0 nMNPASS
Adenosine A2 receptorRattus norvegicusP30543= 37.0 nM|= 5.0 nMNPASS
Adenosine A1 receptorRattus norvegicusP25099= 1949.84 nM= 12.8 nM|= 5.1 nM|= 10.0 nM|= 29000.0 nM|= 870.96 nMNPASS
Adenosine A1 receptorHomo sapiensP30542= 310.0 nM|= 1410.0 nM|= 39.0 nM|= 2511.89 nM|= 69.18 nM= 2.344 nM= 295.12 nM= 812.83 nMNPASS
Adenosine A1 receptorCavia porcellusP47745= 3388.44 nMNPASS
Equilibrative nucleoside transporter 1Homo sapiensQ99808= 63000.0 nM17000 nM|= 17000.0 nM12000 nM|= 12000.0 nMBindingDB, NPASS
Adenosine A2b receptorHomo sapiensP29275= 24000.0 nM|= 51286.14 nM|= 23500.0 nM|= 52.48 nMNPASS
Adenosine receptor A2a/A2bHomo sapiensP29274|P2927551 nMBindingDB
Adenosine A2 receptorHomo sapiensP29274= 51.29 nMNPASS
Adenosine receptor A2bHomo sapiensP2927524000 nM|23500 nM|51286 nM|52 nMBindingDB
Adenosine receptor A2a/A2bRattus norvegicusP29276|P3054337 nM|5 nMBindingDB
EndoplasminHomo sapiensP14625>50000 nM|> 50000.0 nM>10000 nM|> 10000.0 nMBindingDB, NPASS
Cyclin-dependent kinase 2Homo sapiensP24941= 184000.0 nMNPASS
Cavia porcellusCavia porcellus= 570000.0 nM|= 460000.0 nM|= 550000.0 nM|= 340000.0 nMNPASS
Epidermal growth factor receptorHomo sapiensP00533195000 nMBindingDB
Canis familiarisCanis lupus familiaris= 0.12 nMNPASS
CaM kinase I alphaZea maysO04417= 116000.0 nMNPASS
AvidinGallus gallusP02701117000 nM|= 117000.0 nMBindingDB, NPASS
Calcium dependent protein kinaseZea mays116000 nMBindingDB
Adenylate kinase 2, mitochondrialRattus norvegicusP2941092000000 nM|87000000 nMBindingDB
Adenylate kinase 2Rattus norvegicusP29410= 92000000.0 nM|= 87000000.0 nMNPASS
Adenylate kinase 1Rattus norvegicusP39069= 19000000.0 nM|= 82000000.0 nM|= 580000.0 nMNPASS
Adenylate cyclase type VRattus norvegicusQ04400> 300000.0 nMNPASS
Adenylate cyclase type 5Rattus norvegicusQ04400>300000 nMBindingDB
Adenosine receptor A3Rattus norvegicusP28647100 nMBindingDB
Adenosine receptor A3Homo sapiensP0DMS8290 nM|1040 nM|13 nM1.1 nM740 nM290 nMBindingDB
Adenylate kinase isoenzyme 1Rattus norvegicusP3906982000000 nM|19000000 nM|580000 nMBindingDB