IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

Bioactivity information

Target name	Target organism	UniProt identifier	EC50	IC50	Kd	Ki	Source
Sodium-dependent dopamine transporter	Homo sapiens	Q01959				>10000 nM	BindingDB
Sodium channel protein type 1/2/3 subunit alpha	Homo sapiens	P35498\|Q99250\|Q9NY46		1600 nM			BindingDB
Sodium channel alpha subunits; brain (Types I, II, III)	Homo sapiens	Q9NY46		= 1600.0 nM			NPASS
Serotonin 2a (5-HT2a) receptor	Homo sapiens	P28223				> 1000.0 nM	NPASS
SARS-CoV	Severe acute respiratory syndrome-related coronavirus			= 3400.0 nM			NPASS
P-glycoprotein 1	Mus musculus	P06795				= 17900.0 nM	NPASS
Quinolone resistance protein NorA	Staphylococcus aureus	P0A0J7		7000 nM\|9000 nM\|8200 nM\|9200 nM\|8000 nM			BindingDB
Plasmodium falciparum	Plasmodium falciparum			= 1995.26 nM\|= 316.23 nM\|= 2511.89 nM\|= 1258.93 nM\|= 794.33 nM			NPASS
P-glycoprotein 3	Mus musculus	P21447				= 4030.0 nM	NPASS
Solute carrier family 22 member 1	Rattus norvegicus	Q63089				>20000 nM\|> 20000.0 nM	BindingDB, NPASS
Quinolone resistance protein norA	Staphylococcus aureus	P0A0J7		= 8000.0 nM\|= 7000.0 nM\|= 8200.0 nM\|= 9200.0 nM\|= 9000.0 nM			NPASS
Synaptic vesicular amine transporter	Bos taurus	Q27963				1 nM\|= 1.0 nM	BindingDB, NPASS
Synaptic vesicular amine transporter [V132G]	Rat	Q01827		>100 nM			BindingDB
Synaptic vesicular amine transporter	Mus musculus	Q8BRU6		1.8 nM\|= 1.79 nM			BindingDB, NPASS
Synaptic vesicular amine transporter	Rat	Q01827		2.5 nM			BindingDB
Synaptic vesicular amine transporter [G308A]	Rat	Q01827		4.5 nM			BindingDB
Synaptic vesicular amine transporter [G308P]	Rat	Q01827		2 nM			BindingDB
Synaptic vesicular amine transporter [P314G]	Rat	Q01827		3.8 nM			BindingDB
Synaptic vesicular amine transporter [P314L]	Rat	Q01827		4.9 nM			BindingDB
Synaptic vesicular amine transporter [P314T]	Rat	Q01827		4.3 nM			BindingDB
Synaptic vesicular amine transporter [V132A]	Rat	Q01827		>50 nM			BindingDB
Multidrug resistance-associated protein 4	Homo sapiens	O15439		> 133000.0 nM			NPASS
Synaptic vesicular amine transporter [V41A]	Rat	Q01827		1.3 nM			BindingDB
Synaptic vesicular amine transporter [V41I]	Rat	Q01827		3.7 nM			BindingDB
Vesicular amine transporter 1	Homo sapiens	P54219		= 50.0 nM			NPASS
Synaptic vesicular amine transporter	Homo sapiens	Q05940		13 nM\|= 13.2 nM\|= 15.5 nM	8.0 nM\|= 8.0 nM	5.3 nM\|630 nM\|410 nM\|= 5.26 nM\|= 630.0 nM\|= 410.0 nM	BindingDB, NPASS
Mu opioid receptor	Homo sapiens	P35372		= 4152.0 nM		= 1686.0 nM	NPASS
P-glycoprotein 1	Homo sapiens	P08183		= 3019.95 nM\|= 3235.94 nM\|= 500.0 nM\|= 2100.0 nM\|= 2600.0 nM\|= 3900.0 nM\|= 5300.0 nM\|= 6100.0 nM		= 100.0 nM\|= 970.0 nM\|= 11500.0 nM\|= 12200.0 nM\|= 2310.0 nM	NPASS
HL-60	Homo sapiens			= 67000.0 nM			NPASS
MCF7	Homo sapiens			= 0.037 ug.mL-1\|= 0.31 ug.mL-1\|= 0.003 ug.mL-1			NPASS
5-hydroxytryptamine receptor 2A	Homo sapiens	P28223				>1000 nM	BindingDB
5-hydroxytryptamine receptor 2A	Rattus norvegicus	P14842				3057 nM	BindingDB
5-hydroxytryptamine receptor 2C	Rattus norvegicus	P08909				3098 nM	BindingDB
5-hydroxytryptamine receptor 3A	Mus musculus	P23979				>10000 nM	BindingDB
ATP-binding cassette sub-family C member 2	Homo sapiens	Q92887		68400 nM		295000 nM	BindingDB
ATP-binding cassette sub-family C member 3	Homo sapiens	O15438		>133000 nM			BindingDB
ATP-binding cassette sub-family C member 4	Homo sapiens	O15439		>133000 nM			BindingDB
ATP-binding cassette sub-family G member 2	Homo sapiens	Q9UNQ0		= 26302.68 nM\|= 12600.0 nM\|= 11800.0 nM			NPASS
ATP-dependent translocase ABCB1	Homo sapiens	P08183		3900 nM\|5300 nM\|500 nM\|2100 nM\|6100 nM\|2600 nM\|3020 nM\|3236 nM		100 nM\|970 nM\|12200 nM\|11500 nM\|2310 nM	BindingDB
ATP-dependent translocase ABCB1	Mus musculus	P06795				17900 nM	BindingDB
ATP-dependent translocase ABCB1	Mus musculus	P21447				4030 nM	BindingDB
5-hydroxytryptamine receptor 1A	Homo sapiens	P08908				1832 nM	BindingDB
Arachidonate 15-lipoxygenase	Pseudomonas aeruginosa	Q9I4G8		1.38e+4 nM			BindingDB
Acetylcholinesterase	Homo sapiens	P22303		= 1700.0 nM			NPASS
DNA topoisomerase I	Homo sapiens	P11387		= 160000.0 nM			NPASS
DNA topoisomerase 1	Homo sapiens	P11387		160000 nM			BindingDB
D(3) dopamine receptor	Homo sapiens	P35462				598 nM	BindingDB
D(2) dopamine receptor	Homo sapiens	P14416				586 nM	BindingDB
D(1A) dopamine receptor	Homo sapiens	P21728				3849 nM	BindingDB
Canalicular multispecific organic anion transporter 2	Homo sapiens	O15438		> 133000.0 nM			NPASS
Canalicular multispecific organic anion transporter 1	Homo sapiens	Q92887		= 68400.0 nM		= 295000.0 nM	NPASS
Butyrylcholinesterase	Homo sapiens	P06276		= 2800.0 nM			NPASS
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens	Q9UNQ0		26302.68 nM\|12600 nM\|11800 nM			BindingDB
Cystic fibrosis transmembrane conductance regulator	Human	P13569	>50000 nM				BindingDB
Bile salt export pump	Homo sapiens	O95342		8400 nM\|<10000 nM\|8350 nM\|10200 nM\|= 10200.0 nM\|= 8400.0 nM\|< 10000.0 nM\|= 8350.0 nM			BindingDB, NPASS

a curated database

IMPPAT Phytochemical information:
Reserpine

Bioactivity information

IMPPAT Phytochemical information: Reserpine

Bioactivity information

IMPPAT Phytochemical information:
Reserpine