IMPPAT Phytochemical information: 
Cucurbitacin B
Cucurbitacin B
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
VeroChlorocebus aethiops= 40.0 nMNPASS
LNCaPHomo sapiens= 100.0 nMNPASS
SK-OV-3Homo sapiens= 47.0 nMNPASS
Plasmodium falciparumPlasmodium falciparum= 1390.0 nMNPASS
PC-3Homo sapiens= 100.0 nMNPASS
PANC-1Homo sapiens= 67.0 nMNPASS
MDA-MB-231Homo sapiens= 37.0 nMNPASS
MCF7Homo sapiens= 12000.0 nM|= 9720.0 nM|= 40.0 nMNPASS
L02Homo sapiens= 11.0 nMNPASS
HepG2Homo sapiens= 51.0 nMNPASS
HeLaHomo sapiens= 24.0 nMNPASS
HCT-116Homo sapiens= 19.0 nMNPASS
CHOCricetulus griseus= 1990.0 nMNPASS
CFPAC-1Homo sapiens= 23.0 nMNPASS
BXPC-3Homo sapiens= 22.0 nMNPASS
A549Homo sapiens= 88.0 nMNPASS
Insulin-like growth factor 2 mRNA-binding protein 1Homo sapiensQ9NZI8= 66.2 nMNPASS