IMPPAT Phytochemical information: 
5-Hydroxy-7,8-dimethoxyflavone
5-Hydroxy-7,8-dimethoxyflavone
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Serine/threonine-protein kinase PLK1Homo sapiensP5335010200 nM|= 10200.0 nMBindingDB, NPASS
AcetylcholinesteraseHomo sapiensP22303= 2460.0 nMNPASS
Beta-secretase 1Homo sapiensP56817= 2910.0 nMNPASS
HT-22Mus musculus> 100000.0 nMNPASS
HT-29Homo sapiens> 20000.0 nMNPASS
HepG2Homo sapiens= 2720.0 nMNPASS
NON-PROTEIN TARGET> 20000.0 nMNPASS
SW480Homo sapiens> 20000.0 nMNPASS
Serine/threonine-protein kinase PLK2Homo sapiensQ9NYY3951900 nM|= 951900.0 nMBindingDB, NPASS
Serine/threonine-protein kinase PLK3Homo sapiensQ9H4B45123000 nM|= 5123000.0 nMBindingDB, NPASS