IMPPAT Phytochemical information: 
Hyoscyamine
Hyoscyamine
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Muscarinic acetylcholine receptor M2Rattus norvegicusP109801.5 nM|0.99 nM|0.79 nM|1.64 nM|0.78 nM|1.41 nM|1 nM|21 nM|0.98 nM|>10000 nM|0.08 nM|0.87 nM|7600 nMBindingDB
Nicotinic acetylcholine receptorRattus leucopus>10000 nMBindingDB
Muscarinic acetylcholine receptor M5Homo sapiensP089121.7 nM|0.21 nM|0.4 nM|0.5 nM|0.54 nM|0.6 nM|3.0 nMBindingDB
Muscarinic acetylcholine receptor M4Rattus norvegicusP084851.1 nMBindingDB
Muscarinic acetylcholine receptor M4Homo sapiensP081730.6 nM|1 nM|0.3 nM|0.34 nM|0.1 nMBindingDB
Muscarinic acetylcholine receptor M4Gallus gallusP172000.71 nMBindingDB
Muscarinic acetylcholine receptor M3Rattus norvegicusP084830.40 nM|0.31 nM|1 nM|2.1 nM|2 nMBindingDB
Muscarinic acetylcholine receptor M3Homo sapiensP203091.1 nM|0.15 nM|0.1 nM|0.8 nM|0.5 nM|0.2 nMBindingDB
Muscarinic acetylcholine receptor M2Homo sapiensP081720.9 nM|1.5 nM|0.28 nM|2.38 nM|2.4 nM|1.96 nM|0.63 nM|1 nM|5.0 nM|2.8 nM|13 nM|3.6 nM|4.6 nMBindingDB
Muscarinic acetylcholine receptor M2Sus scrofaP061990.39 nM|0.68 nM|1.7 nMBindingDB
Muscarinic acetylcholine receptor M1Homo sapiensP112290.51 nM|0.29 nM|0.7 nM|0.25 nM|1.1 nM|0.2 nMBindingDB
Muscarinic acetylcholine receptor M1Rattus norvegicusP084820.53 nM|0.52 nM|0.32 nM|0.55 nM|0.21 nM|0.28 nM|1 nMBindingDB
Muscarinic acetylcholine receptorOryctolagus cuniculus0.28 nMBindingDB
Histamine H1 receptorRattus norvegicusP313902000 nMBindingDB
Histamine H1 receptorHomo sapiensP353671600 nMBindingDB
D(1A) dopamine receptorBos taurusQ95136>10000 nMBindingDB
Bile salt export pumpHomo sapiensO95342>1000000 nMBindingDB
Beta-arrestin-1Oryctolagus cuniculusQ952230.18 nM|6.8 nMBindingDB
Alpha-1A adrenergic receptorRattus norvegicusP43140>60000 nM|660 nMBindingDB