| Target name | Target organism | UniProt identifier | EC50 | IC50 | Kd | Ki | Source |
|---|
| Melatonin receptor type 1A | Homo sapiens | P48039 | | | | 7100 nM | BindingDB |
| Melatonin receptor 1B | Homo sapiens | P49286 | | | | = 9100.0 nM | NPASS |
| Melatonin receptor 1A | Homo sapiens | P48039 | | | | = 7100.0 nM | NPASS |
| M18 aspartyl aminopeptidase | Plasmodium falciparum (isolate 3D7) | | | 1979 nM | | | BindingDB |
| Lysine-specific demethylase 4D-like | Homo sapiens | B2RXH2 | | = 3000.0 nM | | | NPASS |
| Glutamate carboxypeptidase 2 | Homo sapiens | Q04609 | | >100000 nM | | | BindingDB |
| Dopamine transporter | Rattus norvegicus | P23977 | | = 200.0 nM | | > 5000.0 nM | NPASS |
| Dopamine transporter | Homo sapiens | Q01959 | | = 460.0 nM | | = 6400.0 nM | NPASS |
| Dopamine receptor D4 | Canis lupus familiaris | | | | | 7.5 nM|28 nM | BindingDB |
| Dopamine receptor D2 and D3 | Rattus norvegicus | P61169 | | = 483.0 nM|= 582.0 nM | | | NPASS |
| Dopamine D1 receptor | Homo sapiens | P21728 | = 100.0 nM|= 120.0 nM|= 35.0 nM|= 20.0 nM|= 39.0 nM|= 232.0 nM|= 44.0 nM|= 1400.0 nM|= 2.6 nM | | = 2500.0 nM | = 192.0 nM|= 18200.0 nM|= 130.0 nM|= 124.0 nM|= 12000.0 nM|= 4470.0 nM|= 243.0 nM | NPASS |
| Dopamine receptor | Bos taurus | P20288 | | = 64.0 nM|= 1700.0 nM|= 4.5 nM|= 3.7 nM|> 10000.0 nM|= 150000.0 nM|= 510.0 nM | | | NPASS |
| Dopamine receptor | Homo sapiens | P21728 | | = 15.0 nM | | | NPASS |
| Dopamine D5 receptor | Homo sapiens | P21918 | = 2.0 nM | | | = 2440.0 nM | NPASS |
| Dopamine D4 receptor | Rattus norvegicus | P30729 | = 2.7 nM|= 2.4 nM | | | | NPASS |
| Dopamine D4 receptor | Homo sapiens | P21917 | = 2.2 nM|= 10.0 nM|= 12.3 nM|= 91.2 nM|= 1.8 nM|= 3.78 nM|= 20.89 nM|= 14.79 nM|= 269.15 nM | = 114.0 nM | | = 1.2 nM|= 62.0 nM|= 57.0 nM|= 97.0 nM|= 6.2 nM|= 8.9 nM | NPASS |
| Dopamine D3 receptor | Rattus norvegicus | P19020 | | = 111.0 nM|= 124.0 nM | | = 11.0 nM|= 49.3 nM|= 101.0 nM | NPASS |
| Dopamine D3 receptor | Homo sapiens | P35462 | = 8.53 nM|= 4.76 nM|= 8.57 nM|= 6.1 nM|= 5.8 nM|= 1.8 nM|= 7.64 nM|= 10.6 nM|= 9.333 nM|= 9.3 nM|= 5.34 nM|= 2.7 nM|= 2.1 nM|= 0.11 nM|= 33.0 nM|= 6.4 nM|= 2.3 nM|= 1.1 nM|= 3.5 nM|= 2.9 nM|= 55.0 nM|= 820.0 nM|= 7.26 nM|= 4.0 nM|= 1.6 nM|= 0.6761 nM|= 0.68 nM|= 6.13 nM|= 0.8913 nM|= 4.27 nM | | | = 13.2 nM|= 50.0 nM|= 1600.0 nM|= 52.0 nM|= 290.0 nM|= 240.0 nM|= 72.0 nM|= 1100.0 nM|> 80000.0 nM|= 15.0 nM|= 20.0 nM|= 21.0 nM|= 7.58 nM|= 293.0 nM|= 2.97 nM | NPASS |
| Dopamine D2 receptor | Rattus norvegicus | P61169 | = 8.0 nM|= 1.1 nM|= 5.0 nM|= 1425.0 nM | = 1860.0 nM|= 1700.0 nM|= 1200.0 nM|= 5340.0 nM|= 2200.0 nM|= 1500.0 nM|= 3045.0 nM|= 3500.0 nM|= 3260.0 nM|= 3140.0 nM | = 6200.0 nM|= 267000.0 nM|= 37000.0 nM|= 49000.0 nM|= 17000.0 nM | = 724.44 nM|= 104.71 nM|= 15.0 nM|= 843.0 nM|> 1000.0 nM|= 296.0 nM|= 197.0 nM|= 990.0 nM | NPASS |
| Dopamine D2 receptor | Homo sapiens | P14416 | = 170.0 nM|= 18.0 nM|= 8.0 nM|= 209.0 nM|= 43.0 nM|= 227.0 nM|= 65.0 nM|= 240.0 nM|= 6.7 nM|= 36.0 nM|= 218.0 nM|= 467.74 nM|= 470.0 nM|= 183.0 nM|= 5.0 nM|= 7.7 nM|= 0.69 nM|= 2.8 nM|= 3.9 nM|= 4.5 nM|= 0.67 nM|= 0.78 nM|= 226.0 nM|= 163.0 nM|= 156.0 nM|= 390.0 nM|= 200.0 nM|= 160.0 nM|= 19.0 nM|= 0.99 nM|= 40.0 nM|= 140.0 nM|= 376.0 nM|= 0.8 nM|= 18.2 nM|= 200.41 nM|= 57.1 nM|= 66.07 nM|= 66.25 nM|= 3460.0 nM | = 8e-06 nM | | = 1.89 nM|= 759.0 nM|= 572.0 nM|= 7940.0 nM|= 20.0 nM|= 17.0 nM|= 1900.0 nM|= 1100.0 nM|= 42.0 nM|= 34.0 nM|= 15000.0 nM|= 260.0 nM|= 450.0 nM|= 360.0 nM|= 2100.0 nM|= 2.9 nM|= 422.0 nM|= 110.0 nM|= 190.0 nM|= 8.0 nM|= 8.73 nM|= 3690.0 nM|= 48.0 nM|= 16.0 nM | NPASS |
| Dopamine D2 receptor | Bos taurus | P20288 | | = 8000.0 nM|= 4700.0 nM | | = 11.0 nM|= 1.8 nM|= 1600.0 nM|= 51.0 nM|= 12000000.0 nM|= 14.9 nM|= 1520.0 nM|= 617.0 nM|= 2350.0 nM|= 34.0 nM|= 3380.0 nM | NPASS |
| Dopamine D1 receptor | Rattus norvegicus | P18901 | = 3500.0 nM|= 5000.0 nM | = 3000.0 nM|= 800.0 nM|= 3700.0 nM | | = 416.87 nM|= 309.03 nM|= 4400.0 nM|= 150.0 nM|> 1000.0 nM | NPASS |
| Melatonin receptor type 1B | Homo sapiens | P49286 | | | | 9100 nM | BindingDB |
| Dopamine receptor | Rattus norvegicus | P61169 | | = 2.0 nM|= 2.1 nM|= 5340.0 nM | | | NPASS |
| Mus musculus | Mus musculus | | | = 10000.0 nM | | | NPASS |
| Sodium-dependent dopamine transporter | Rattus norvegicus | P23977 | | 200 nM | | 230 nM|38.3 nM|>5000 nM | BindingDB |
| Norepinephrine transporter | Homo sapiens | P23975 | | = 6.63 nM | | > 28000.0 nM | NPASS |
| Dopamine D1 receptor | Bos taurus | Q95136 | | = 200.0 nM | | = 4300.0 nM|= 7.0 nM|= 650.0 nM|= 36.0 nM|= 1600.0 nM|= 440.0 nM | NPASS |
| cyclic AMP phosphoprotein | Rattus norvegicus | Q712U5 | = 3500.0 nM | | | | NPASS |
| cAMP-regulated phosphoprotein 19 | Rattus norvegicus | Q712U5 | 3500 nM | | | | BindingDB |
| Tyrosine-protein kinase Fyn | Homo sapiens | P06241 | | >100000 nM | | | BindingDB |
| Tyrosine-protein kinase FYN | Homo sapiens | P06241 | | > 100000.0 nM | | | NPASS |
| Trace amine-associated receptor 1 | Homo sapiens | Q96RJ0 | 1710 nM|= 1710.0 nM | | | 422 nM | BindingDB, NPASS |
| Solute carrier family 22 member 3 | Rattus norvegicus | O88446 | | 62000 nM|384000 nM|= 384000.0 nM|= 62000.0 nM | | | BindingDB, NPASS |
| Solute carrier family 22 member 2 | Rattus norvegicus | Q9R0W2 | | 2300000 nM|= 2300000.0 nM | | 347000 nM|= 347000.0 nM | BindingDB, NPASS |
| Solute carrier family 22 member 1 | Rattus norvegicus | Q63089 | | | | 603000 nM|= 603000.0 nM | BindingDB, NPASS |
| Sodium-dependent serotonin transporter | Rattus norvegicus | P31652 | | | | 1000 nM|6489 nM | BindingDB |
| Sodium-dependent serotonin transporter | Homo sapiens | P31645 | | >30000 nM | | >1100000 nM | BindingDB |
| NON-PROTEIN TARGET | | | | = 68900.0 nM|> 10000.0 nM | | | NPASS |
| Sodium-dependent noradrenaline transporter | Homo sapiens | P23975 | | 6.6 nM | | 323 nM|>28000 nM | BindingDB |
| Sodium-dependent dopamine transporter | Homo sapiens | Q01959 | | 460 nM | | 1770 nM|5300 nM|5900 nM|67 nM|3100 nM|6400 nM | BindingDB |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus | Q9R0C9 | | | | >10000 nM | BindingDB |
| Serotonin transporter | Homo sapiens | P31645 | | > 30000.0 nM | | > 1100000.0 nM | NPASS |
| Serotonin 1a (5-HT1a) receptor | Rattus norvegicus | P19327 | | | | > 10000.0 nM | NPASS |
| SARS-CoV-2 | Severe acute respiratory syndrome coronavirus 2 | | | > 20000.0 nM|> 19952.62 nM | | | NPASS |
| Rattus norvegicus | Rattus norvegicus | | = 3500.0 nM | = 29.0 nM | | > 3000.0 nM|= 1437.0 nM|= 5268.0 nM | NPASS |
| RAW264.7 | Mus musculus | | = 18000.0 nM | | | | NPASS |
| Procathepsin L | Homo sapiens | P07711 | | >59642 nM | | | BindingDB |
| Oryctolagus cuniculus | Oryctolagus cuniculus | | = 38.0 nM|= 73.0 nM|= 76.0 nM | | | | NPASS |
| Opioid receptor | Rattus norvegicus | P33535 | | = 3045.0 nM | | | NPASS |
| Norepinephrine transporter | Rattus norvegicus | | | | | 1000 nM|392 nM|40.3 nM | BindingDB |
| Sodium-dependent noradrenaline transporter | Bos taurus | P51143 | | | | 397 nM | BindingDB |
| Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1 | Rattus norvegicus | P33533|P33535|P34975|Q9R0C9 | | 3045 nM | | | BindingDB |
| Alpha-2C adrenergic receptor | Rattus norvegicus | P22086 | | | | >10000 nM|9989 nM | BindingDB |
| D(4) dopamine receptor | Homo sapiens | P21917 | 2.2 nM|2.7 nM|10 nM|12 nM|91 nM|1.8 nM|15 nM|21 nM|269 nM | | | 42.9 nM|180 nM|407 nM|6.2 nM|1.2 nM|62 nM|97 nM|57 nM|3310 nM | BindingDB |
| Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor | Rattus norvegicus | P15823|P23944|P43140 | | 90000 nM | | | BindingDB |
| Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor | Homo sapiens | P25100|P35348|P35368 | | | | 2512 nM | BindingDB |
| Alpha-1A adrenergic receptor | Rattus norvegicus | P43140 | | | | 250 nM|44000 nM | BindingDB |
| Adrenergic receptor alpha-2 | Rattus norvegicus | P22909 | | | | = 58.0 nM | NPASS |
| Adrenergic receptor alpha-1 | Rattus norvegicus | P43140 | | = 90000.0 nM | | = 14000.0 nM | NPASS |
| Adrenergic receptor alpha-1 | Homo sapiens | P35368 | | | | = 2511.89 nM | NPASS |
| Adenylate cyclase type 1 | Rattus norvegicus | | 3500 nM | | | | BindingDB |
| Adenylate cyclase | Rattus norvegicus | P21932 | = 3500.0 nM | | | | NPASS |
| Adenosine receptor A2b | Rattus norvegicus | P29276 | | | | 977 nM | BindingDB |
| Adenosine A2b receptor | Rattus norvegicus | P29276 | | | | = 977.24 nM | NPASS |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus | P32305 | | | | 240 nM|>10000 nM|1000 nM|545 nM | BindingDB |
| 5-hydroxytryptamine receptor 6 | Mus musculus | Q9R1C8 | | | | >10000 nM | BindingDB |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus | P35365 | | | | 1000 nM | BindingDB |
| 5-hydroxytryptamine receptor 5B | Mus musculus | P31387 | | | | >10000 nM | BindingDB |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus | P35364 | | | | 1000 nM | BindingDB |
| 5-hydroxytryptamine receptor 5A | Mus musculus | P30966 | | | | >10000 nM | BindingDB |
| 5-hydroxytryptamine receptor 3A | Mus musculus | P23979 | | | | >10000 nM | BindingDB |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus | P08909 | | | | >10000 nM | BindingDB |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus | P14842 | | | | >10000 nM | BindingDB |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus | P19327 | | | | >10000 nM|545 nM | BindingDB |
| 5-hydroxytryptamine receptor 1A | Oryctolagus cuniculus | | | | | 7800 nM | BindingDB |
| 5-hydroxytryptamine receptor 1A | Homo sapiens | P08908 | | | | 8248 nM | BindingDB |
| D(4) dopamine receptor | Rattus norvegicus | P30729 | 2.4 nM|2.7 nM | | | | BindingDB |
| Alpha-synuclein | Homo sapiens | P37840 | | 7100 nM|530 nM|= 7100.0 nM|= 530.0 nM | | | BindingDB, NPASS |
| Anthrax toxin receptor 2 | Homo sapiens | P58335 | | >300000 nM|> 300000.0 nM | | | BindingDB, NPASS |
| 5-hydroxytryptamine receptor 7 | Homo sapiens | P34969 | | | | >10000 nM | BindingDB |
| Beta-1 adrenergic receptor | Rattus norvegicus | P18090 | | | | 10000 nM|= 10000.0 nM | BindingDB, NPASS |
| D(2) dopamine receptor | Rattus norvegicus | P61169 | 1.1 nM|1425 nM|8 nM|5 nM | 3045 nM|1700 nM|1860 nM|1200 nM|5340 nM|1500 nM|2200 nM|3500 nM|3260 nM|3140 nM | 267000 nM|49000 nM|6200 nM|17000 nM|37000 nM | 594 nM|51 nM|2.8 nM|474 nM|8912.5 nM|660 nM|211 nM|2627 nM|310 nM|210 nM|192 nM|197 nM|105 nM|15 nM|296 nM|843 nM|>1000 nM|724 nM|990 nM | BindingDB |
| D(2) dopamine receptor | Oryctolagus cuniculus | | | | | 250 nM|200 nM | BindingDB |
| D(2) dopamine receptor | Mus musculus | P61168 | | | | 1949.84 nM | BindingDB |
| D(2) dopamine receptor | Homo sapiens | P14416 | 18 nM|470 nM|8 nM|209 nM|5.0 nM|7.7 nM|0.690000 nM|0.780 nM|0.780000 nM|163 nM|156 nM|4.5 nM|3.9 nM|226 nM|2.8 nM|200 nM|160 nM|390 nM|170 nM|43 nM|227 nM|65 nM|240 nM|6.7 nM|36 nM|0.631000 nM|218 nM|19 nM|183 nM|0.990000 nM|40 nM|140 nM|376 nM|0.800000 nM | 0.000 nM|100000 nM|1000 nM | | 544 nM|>10000 nM|710 nM|880 nM|422 nM|1606 nM|1.9 nM|260 nM|572 nM|759 nM|450 nM|360 nM|3690 nM|8.7 nM|48 nM|16 nM|7940 nM|34 nM|15000 nM|17 nM|20 nM|1100 nM|42 nM|1900 nM|2100 nM|2.9 nM|110 nM|190 nM|8.0 nM|920 nM|11600 nM|231 nM|871 nM|22 nM|56 nM|2.0 nM | BindingDB |
| D(2) dopamine receptor | Canis lupus familiaris | Q9GJU1 | | | | >10000 nM | BindingDB |
| D(2) dopamine receptor | Bos taurus | P20288 | | 4700 nM|8000 nM | | 670 nM|550 nM|700 nM|475 nM|3380 nM|34 nM|1520 nM|617 nM|2350 nM|15 nM|12000000 nM|1.8 nM|11 nM|51 nM|1600 nM | BindingDB |
| D(1B) dopamine receptor | Rattus norvegicus | P25115 | | | | 3900 nM | BindingDB |
| D(1B) dopamine receptor | Homo sapiens | P21918 | 2.0 nM | | | 228 nM|2440 nM | BindingDB |
| D(1A)/D(2) dopamine receptor | Bos taurus | P20288|Q95136 | | 1700 nM|64 nM|150000 nM|510 nM|4.5 nM|>10000 nM|3.7 nM | | | BindingDB |
| D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor | Rattus norvegicus | P18901|P19020|P25115|P30729|P61169 | | 2.1 nM|2.0 nM|5340 nM | | | BindingDB |
| D(3) dopamine receptor | Homo sapiens | P35462 | 9.3 nM|8.53 nM|1.8 nM|2.7 nM|4.76 nM|8.6 nM|6.1 nM|5.8 nM|2.1 nM|5.3 nM|0.110000 nM|6.4 nM|1.1 nM|2.3 nM|3.5 nM|33 nM|2.9 nM|820 nM|55 nM|7.3 nM|0.891251 nM | | | 23 nM|29 nM|20 nM|54.95 nM|104 nM|33.9 nM|13.2 nM|240 nM|72 nM|7.6 nM|293 nM|3.0 nM|52 nM|50 nM|1600 nM|290 nM|15 nM|21 nM | BindingDB |
| D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor | Homo sapiens | P14416|P21728|P21917|P21918|P35462 | | 15 nM | | | BindingDB |
| D(1A) dopamine receptor | Homo sapiens | P21728 | 20 nM|37 nM|100 nM|120 nM|35 nM|232 nM|1400 nM|44 nM | | 2500 nM | 2340 nM|>10000 nM|4470 nM|130 nM|124 nM|192 nM|18200 nM|12000 nM|243 nM | BindingDB |
| D(1A) dopamine receptor | Bos taurus | Q95136 | | 200 nM | | 17.5 nM|16.8 nM|11.7 nM|51.44 nM|>10000 nM|4300 nM|650 nM|36 nM|1600 nM|7 nM|440 nM | BindingDB |
| Cavia porcellus | Cavia porcellus | | = 1500.0 nM|= 1700.0 nM | | | | NPASS |
| Cannabinoid receptor 1 | Hirudo medicinalis | | | | | 1000 nM | BindingDB |
| CB1 cannabinoid receptor-interacting protein 1 | Theromyzon tessulatum | | | | | 1000 nM | BindingDB |
| Bile salt export pump | Rattus norvegicus | O70127 | | >1000000 nM|> 1000000.0 nM | | | BindingDB, NPASS |
| Bile salt export pump | Homo sapiens | O95342 | | >1000000 nM|> 1000000.0 nM | | | BindingDB, NPASS |
| Beta-2 adrenergic receptor | Homo sapiens | P07550 | | | 64560 nM|= 64560.0 nM | >10000 nM|61000 nM|= 61000.0 nM | BindingDB, NPASS |
| Beta-2 adrenergic receptor | Canis lupus familiaris | P54833 | | | | 50000 nM|= 50000.0 nM | BindingDB, NPASS |
| D(3) dopamine receptor | Rattus norvegicus | P19020 | | 111 nM|124 nM | | 25 nM|265.7 nM|49 nM|11 nM|101 nM | BindingDB |
| D(1A) dopamine receptor | Rattus norvegicus | P18901 | 3500 nM|5000 nM | 800 nM|3000 nM|3700 nM | | 380 nM|1450 nM|220 nM|1000 nM|309 nM|4400 nM|150 nM|>1000 nM|417 nM | BindingDB |
| Arginase-1 | Bos taurus | Q2KJ64 | | 128000 nM|= 128000.0 nM | | | BindingDB, NPASS |
