IMPPAT Phytochemical information: 
Arbutin
Arbutin
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Polyphenol oxidase 2Agaricus bisporusO4271324000000 nM|10400000 nM|7300000 nM|100000 nM|>1000000 nM|210000 nM|201200 nM|5300000 nM|146000 nM|194500 nM|366000 nM|560000 nM|10400 nMBindingDB
TyrosinaseMus musculusP1134430260 nM|1550000 nM|87500 nM|500000 nM|= 30260.0 nM|= 1550000.0 nM|= 87500.0 nM|= 500000.0 nMBindingDB, NPASS
TyrosinaseHomo sapiensP14679230000 nM|30260 nM|32000000 nM|>1600 nM|164000 nM|6500000 nM|= 32000000.0 nM|= 30260.0 nM|= 230000.0 nM|> 1600.0 nM|= 164000.0 nM|= 6500000.0 nM|> 4000000.0 nMBindingDB, NPASS
SARS-CoV-2Severe acute respiratory syndrome coronavirus 2> 20000.0 nM|> 19952.62 nMNPASS
Polyphenol oxidase 1White button mushroomQ000243.20e+5 nMBindingDB
TyrosinaseAgaricus bisporusO42713= 10400000.0 nM|= 24000000.0 nM|= 7300000.0 nM|> 1000000.0 nM|= 210000.0 nM|= 2300.0 ppm|= 201200.0 nM|= 5300000.0 nM|= 146000.0 nM|= 194500.0 nM|= 100000.0 nM|= 366000.0 nM|= 560000.0 nM|= 10400.0 nMNPASS
NON-PROTEIN TARGET> 1000000.0 nMNPASS
Melan-aMus musculus= 98050.0 nMNPASS
B16-F10Mus musculus= 391200.0 nMNPASS
B16-F1Mus musculus= 148300.0 nM|= 122000.0 nMNPASS
B16Mus musculus= 116000.0 nM|= 180000.0 nM|= 120000.0 nM|= 99000.0 nM|= 67.9 ug.mL-1|= 140000.0 nM|= 400000.0 nM|= 247000.0 nM|= 64000.0 nMNPASS
P388Mus musculus> 25.0 ug.mL-1NPASS