IMPPAT Phytochemical information: 
Isoguvacine
Isoguvacine
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2Homo sapiensP14867|P18507|P28472160000 nMBindingDB
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2Homo sapiensP18507|P47869|P478704500 nM|4467 nMBindingDB
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2Homo sapiensP18507|P34903|P478705600 nM|5623 nMBindingDB
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2Homo sapiensP18507|P28472|P3490355000 nMBindingDB
Gamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2Homo sapiensP18507|P28472|Q1644520000 nMBindingDB
SARS-CoV-2Severe acute respiratory syndrome coronavirus 2> 20000.0 nM|> 19952.62 nMNPASS
Gamma-aminobutyric acid receptor subunit rho-3Homo sapiensA8MPY1>10000 nMBindingDB
Gamma-aminobutyric acid type B receptor subunit 1/2O88871|Q9Z0U4>100000 nMBindingDB
Proton-coupled amino acid transporter 1Homo sapiensQ7Z2H85800000 nM|= 5800000.0 nMBindingDB, NPASS
Rattus norvegicusRattus norvegicus= 13000.0 nM> 300000.0 nMNPASS
GABA-A receptor; anion channelRattus norvegicusQ9ES14= 3100.0 nM= 22.0 nM|= 490.0 nMNPASS
Gamma-aminobutyric acid receptor subunit rho-1Homo sapiensP2404639000 nM|38905 nMBindingDB
GABA-A receptor; anion channelHomo sapiensQ16445= 310000.0 nM= 54.95 nM|= 55.0 nMNPASS
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2Homo sapiensP14867|P18507|P4787011000 nM|11220 nMBindingDB
GABA-A receptor; alpha-5/beta-3/gamma-2Homo sapiensP31644= 75000.0 nMNPASS
GABA-A receptor; alpha-6/beta-3/gamma-2Homo sapiensQ16445= 20000.0 nMNPASS
GABA A receptor alpha-2/beta-2/gamma-2Homo sapiensP47869= 4500.0 nM|= 4466.84 nMNPASS
GABA A receptor alpha-3/beta-2/gamma-2Homo sapiensP34903= 5600.0 nM|= 5623.41 nMNPASS
GABA A receptor alpha-4/beta-3/gamma-2Homo sapiensP48169= 180000.0 nMNPASS
GABA B receptorRattus norvegicusO88871> 100000.0 nMNPASS
GABA receptor rho-1 subunitHomo sapiensP24046= 39000.0 nM|= 38904.51 nMNPASS
GABA A receptor alpha-4/beta-3/gamma-2Homo sapiensP18507|P28472|P48169180000 nMBindingDB
GABA-A receptor; alpha-1/beta-3/gamma-2Homo sapiensP28472= 160000.0 nMNPASS
GABA-A receptor; alpha-2/beta-3/gamma-2Homo sapiensP18507|P28472|P4786950000 nMBindingDB
GABA-A receptor; alpha-2/beta-3/gamma-2Homo sapiensP47869= 50000.0 nMNPASS
GABA-A receptor; alpha-3/beta-3/gamma-2Homo sapiensP34903= 55000.0 nMNPASS
GABA-A receptor; alpha-5/beta-3/gamma-2Homo sapiensP18507|P28472|P3164475000 nMBindingDB
GABA-A receptor; alpha-1/beta-2/gamma-2Homo sapiensP18507= 11000.0 nM|= 11220.18 nMNPASS