| Target name | Target organism | UniProt identifier | EC50 | IC50 | Kd | Ki | Source |
|---|
| Ovarian cancer cell line | Homo sapiens | | | >= 40000.0 nM | | | NPASS |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens | O75469 | 30000 nM | | | | BindingDB |
| Multidrug resistance-associated protein 4 | Homo sapiens | O15439 | | > 133000.0 nM | | | NPASS |
| Melanoma cell line | Homo sapiens | | | >= 40000.0 nM | | | NPASS |
| MRC5 | Homo sapiens | | | = 50300.0 nM|> 25000.0 nM | | | NPASS |
| Leishmania major | Leishmamajor | | | = 750.0 nM|= 300.0 nM | | | NPASS |
| MCF7 | Homo sapiens | | | = 0.14 nM|> 50000.0 nM | | | NPASS |
| Leishmania donovani | Leishmadonovani | | | = 30800.0 nM|= 100000.0 nM|> 40000.0 nM|> 100000.0 nM | | | NPASS |
| L6 | Rattus norvegicus | | | = 450500.0 nM|= 450000.0 nM | | | NPASS |
| PC-12 | Rattus norvegicus | | | > 50000.0 nM | | | NPASS |
| MDA-MB-231 | Homo sapiens | | | > 50000.0 nM|> 100000.0 nM|= 39030.0 nM | | | NPASS |
| PC-3 | Homo sapiens | | | = 39030.0 nM | | | NPASS |
| L02 | Homo sapiens | | | > 50000.0 nM|> 100000.0 nM|= 430.0 nM|= 8250.0 nM | | | NPASS |
| Plasmodium falciparum | Plasmodium falciparum | | = 9.3 nM|= 6.0 nM|= 13.0 nM|= 5.0 nM|= 2.0 nM|= 8.0 nM|= 23.0 nM|= 10.0 nM|= 20.0 nM|= 0.8 nM|= 15.0 nM|= 18.0 nM|= 30.0 nM|= 5.4 nM|= 3.6 nM|= 17.3 nM|= 27.0 nM|= 2.4 nM|= 1.0 nM|= 11.0 nM | = 29.0 nM|= 12.0 nM|= 7.0 nM|= 13.0 nM|= 140.0 nM|= 6.2 nM|= 9.0 nM|= 25.0 nM|= 14.0 nM|= 4.0 nM|= 45.0 nM|= 23.0 nM|= 15.0 nM|= 6.0 nM|= 5.9 nM|= 74.0 nM|= 32.1 nM|= 94.0 nM|= 8.5 nM|= 4.1 nM|= 5.2 nM|= 2.2 nM|= 12.1 nM|= 16.3 nM|= 10.0 nM|= 19.0 nM|= 10.4 nM|= 0.013 ug.mL-1|= 0.014 ug.mL-1|= 17.1 nM|= 16.2 nM|= 32.0 nM|= 21.0 nM|= 80.0 nM|= 54.0 nM|= 6.4 nM|= 2.5 nM|= 30.0 nM|= 250.0 nM|= 6.5 nM|= 55.0 nM|= 33.0 nM|= 3.4 nM|= 18.0 nM|= 12000.0 nM|= 22.0 nM|= 11.0 nM|= 26.0 nM|= 20.0 nM|= 1.4 nM|= 0.001 mg/cm3|= 6.6 nM|= 8.0 nM|= 5.32 nM|= 0.81 nM|= 13.04 nM|= 0.6 nM|= 21000.0 nM|= 6.9 nM|= 300.0 nM|= 24000.0 nM|= 6.7 nM|= 5.0 nM|= 12700.0 nM|= 17000.0 nM|= 3.04 nM|= 12.5 nM|= 18.43 nM|= 2.8 nM|= 13.48 nM|= 4.74 nM|= 120.0 nM|= 7.81 nM|= 2.1 nM | | | NPASS |
| Plasmodium falciparum (isolate K1 / Thailand) | Plasmodium falciparum K1 | | | = 6.4 nM | | | NPASS |
| Vero | Chlorocebus aethiops | | | > 16860.0 nM | | | NPASS |
| Plasmodium falciparum D6 | Plasmodium falciparum D6 | | | = 9.0 nM|= 71.0 nM | | | NPASS |
| SARS-CoV-2 | Severe acute respiratory syndrome coronavirus 2 | | | > 20000.0 nM|> 19952.62 nM | | | NPASS |
| SH-SY5Y | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| SMMC-7721 | Homo sapiens | | | = 630.0 nM|= 440.0 nM | | | NPASS |
| Toxoplasma gondii | Toxoplasma gondii | | | = 2000.0 nM | | | NPASS |
| Trypanosoma brucei rhodesiense | Trypanosoma brucei rhodesiense | | | = 20400.0 nM | | | NPASS |
| Trypanosoma cruzi | Trypanosoma cruzi | | | = 13400.0 nM | | | NPASS |
| U-87 MG | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| Plasmodium berghei | Plasmodium berghei | | | = 12000.0 nM|= 8.9 nM | | | NPASS |
| K562 | Homo sapiens | | | = 39030.0 nM | | | NPASS |
| Plasmodium falciparum 3D7 | Plasmodium falciparum 3D7 | | | = 0.001117 ug.mL-1|= 7.75 nM | | | NPASS |
| Hemozoin | Plasmodium falciparum | | | = 0.66 equiv | | | NPASS |
| HepG2 | Homo sapiens | | | > 50000.0 nM|> 300000.0 nM|= 4090.0 nM|= 97000.0 nM | | | NPASS |
| A-375 | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| A-431 | Homo sapiens | | | = 39030.0 nM | | | NPASS |
| A549 | Homo sapiens | | | > 50000.0 nM|= 39030.0 nM|> 300000.0 nM|= 9850.0 nM | | | NPASS |
| ATP-binding cassette sub-family C member 2 | Homo sapiens | Q92887 | | >133000 nM | | | BindingDB |
| ATP-binding cassette sub-family C member 3 | Homo sapiens | O15438 | | >133000 nM | | | BindingDB |
| ATP-binding cassette sub-family C member 4 | Homo sapiens | O15439 | | >133000 nM | | | BindingDB |
| BEAS-2B | Homo sapiens | | | = 7530.0 nM | | | NPASS |
| Bile salt export pump | Homo sapiens | O95342 | | >133000 nM|> 133000.0 nM | | | BindingDB, NPASS |
| Breast carcinoma cell | Homo sapiens | | | >= 40000.0 nM | | | NPASS |
| CAKI-2 | Homo sapiens | | | = 40000.0 nM | | | NPASS |
| CCRF-CEM | Homo sapiens | | = 36900.0 nM | | | | NPASS |
| BT-549 | Homo sapiens | | | = 40000.0 nM | | | NPASS |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens | Q92887 | | > 133000.0 nM | | | NPASS |
| HeLa | Homo sapiens | | | = 493380.0 nM | | | NPASS |
| COLO 205 | Homo sapiens | | | = 39030.0 nM | | | NPASS |
| HL-60 | Homo sapiens | | | = 40000.0 nM | | | NPASS |
| HEK293 | Homo sapiens | | | > 120.0 nM|= 39030.0 nM | | | NPASS |
| HCT-15 | Homo sapiens | | | > 300000.0 nM | | | NPASS |
| HCT-116 | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| HUVEC | Homo sapiens | | | = 1100.0 nM | | | NPASS |
| Dihydroorotate dehydrogenase (fumarate) | Leishmamajor | | | 158489 nM|171900 nM | | | BindingDB |
| Cytochrome P450 3A4 | Homo sapiens | P08684 | 5900 nM | 50000 nM | | 25000 nM | BindingDB |
| Cytochrome P450 2B6 | Homo sapiens | P20813 | 600 nM | 12100 nM|8400 nM | | 4600 nM | BindingDB |
| Canalicular multispecific organic anion transporter 2 | Homo sapiens | O15438 | | > 133000.0 nM | | | NPASS |
| Dihydroorotate dehydrogenase (fumarate) | Leishmamajor | Q4QEW7 | | = 171900.0 nM|= 158489.32 nM | | | NPASS |
