IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

Bioactivity information

Target name	Target organism	UniProt identifier	EC50	IC50	Kd	Ki	Source
NON-PROTEIN TARGET				= 9100.0 nM			NPASS
Mitogen-activated protein kinase 14	Homo sapiens	Q16539		1.14e+4 nM			BindingDB
Mitogen-activated protein kinase 10	Homo sapiens	P53779		2.68e+4 nM			BindingDB
Low molecular weight phosphotyrosine protein phosphatase	Bos taurus	P11064		10000 nM\|= 10000.0 nM			BindingDB, NPASS
Liver microsomes	Rattus norvegicus			= 23000000.0 nM			NPASS
Pancreatic triacylglycerol lipase	Sus scrofa	P00591		>100000 nM\|> 100000.0 nM			BindingDB, NPASS
Lactoylglutathione lyase	Homo sapiens	Q04760				30200 nM	BindingDB
L929	Mus musculus		= 120000.0 nM\|= 115000.0 nM				NPASS
HSP60/HSP10	Homo sapiens			= 11000.0 nM			NPASS
Interstitial collagenase [100-268]	Human	P03956		4.85e+3 nM			BindingDB
Integrase	Human immunodeficiency virus 1			31700 nM\|76500 nM			BindingDB
Induced myeloid leukemia cell differentiation protein Mcl-1	Homo sapiens	Q07820		2988.260716 nM\|= 2988.26 nM			BindingDB, NPASS
Human immunodeficiency virus type 1 integrase	Human immunodeficiency virus 1	Q7ZJM1		= 76500.0 nM\|= 31700.0 nM			NPASS
Human immunodeficiency virus 1	Human immunodeficiency virus 1		< 100000.0 nM\|> 331000.0 nM				NPASS
Histone-lysine N-methyltransferase SETD7	Homo sapiens	Q8WTS6		6020 nM\|= 6020.0 nM			BindingDB, NPASS
Histone deacetylase 6	Homo sapiens	Q9UBN7		= 1610.0 nM			NPASS
Plasmodium falciparum	Plasmodium falciparum			= 110400.0 nM\|= 16100.0 nM			NPASS
H9	Homo sapiens			> 331000.0 nM			NPASS
Islet amyloid polypeptide	Homo sapiens	P10997		7800 nM\|= 7800.0 nM			BindingDB, NPASS
Protein E6	Human papillomavirus type 16	P03126		4000 nM\|= 4000.0 nM			BindingDB, NPASS
Sortase	Staphylococcus aureus	Q9S446		= 37390.0 nM			NPASS
Receptor-type tyrosine-protein phosphatase S	Homo sapiens	Q13332		4300 nM\|= 4300.0 nM			BindingDB, NPASS
GroEL/GroES	Escherichia coli			= 5200.0 nM\|= 8500.0 nM			NPASS
Xanthine dehydrogenase/oxidase	Homo sapiens	P47989		10100 nM			BindingDB
Xanthine dehydrogenase	Homo sapiens	P47989		= 10100.0 nM\|= 25000.0 nM			NPASS
Tyrosine-protein kinase Yes	Homo sapiens	P07947				7900 nM	BindingDB
Tyrosine-protein kinase YES	Homo sapiens	P07947				= 7900.0 nM	NPASS
Tyrosine-protein kinase SYK	Homo sapiens	P43405	>300000 nM\|> 300000.0 nM	28000 nM\|= 28000.0 nM			BindingDB, NPASS
Tubulin	Homo sapiens	Q9BUF5			= 199526.23 nM\|> 100000.0 nM		NPASS
Trypsin I	Bos taurus	P00760		= 110800.0 nM			NPASS
RNA demethylase ALKBH5	Homo sapiens	Q6P6C2		= 7130.0 nM			NPASS
Thiosulfate sulfurtransferase	Homo sapiens	Q16762		57000 nM\|= 57000.0 nM			BindingDB, NPASS
Sortase A	Streptococcus mutans	Q8CM62		= 27200.0 nM			NPASS
Sortase A	Staphylococcus aureus	Q9S446		= 37390.0 nM			NPASS
Solute carrier family 22 member 12	Rattus norvegicus	Q3ZAV1		18000 nM\|= 18000.0 nM			BindingDB, NPASS
Solute carrier family 22 member 12	Homo sapiens	Q96S37		2000 nM\|= 2000.0 nM		5740 nM\|= 5740.0 nM\|= 2000.0 nM	BindingDB, NPASS
Serine/threonine-protein kinase pim-1	Homo sapiens	P11309		2700 nM\|2692 nM			BindingDB
Serine/threonine-protein kinase PLK1	Homo sapiens	P53350		12600 nM\|= 12600.0 nM			BindingDB, NPASS
Serine protease 1	Bos taurus	P00760		110800 nM			BindingDB
SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2			> 20000.0 nM\|> 19952.62 nM			NPASS
Sortase family protein	Staphylococcus aureus			37390 nM\|19000 nM			BindingDB
Glyoxalase I	Homo sapiens	Q04760				= 30199.52 nM	NPASS
Sortase	Streptococcus mutans			27200 nM			BindingDB
G-protein coupled receptor 35	Homo sapiens	Q9HC97	1330 nM\|11200 nM\|= 1330.0 nM\|= 11200.0 nM	1600 nM\|= 1600.0 nM			BindingDB, NPASS
Beta-secretase 1	Homo sapiens	P56817		12300 nM\|21700 nM\|= 12300.0 nM\|= 21700.0 nM			BindingDB, NPASS
Beta amyloid A4 protein	Homo sapiens	P05067		= 30300.0 nM			NPASS
Aurora kinase B	Homo sapiens	Q96GD4		4.71e+3 nM			BindingDB
Amyloid-beta precursor protein	Homo sapiens	P05067		3.03e+4 nM\|30300 nM\|8500 nM			BindingDB
Amyloid-beta A4 protein	Homo sapiens	P05067		= 7400.0 nM			NPASS
Alpha-ketoglutarate-dependent dioxygenase FTO	Homo sapiens	Q9C0B1		= 2580.0 nM			NPASS
Alpha-glucosidase MAL62	Saccharomyces cerevisiae	P07265		39994 nM			BindingDB
Adenosine receptor A3	Homo sapiens	P0DMS8				34000 nM	BindingDB
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens	Q9UNQ0		21000 nM\|49000 nM			BindingDB
Adenosine receptor A1	Rattus norvegicus	P25099				13800 nM	BindingDB
Adenosine A2 receptor	Rattus norvegicus	P30543				= 17300.0 nM	NPASS
Adenosine A1 receptor	Rattus norvegicus	P25099				= 13800.0 nM	NPASS
ATP-binding cassette sub-family G member 2	Homo sapiens	Q9UNQ0		= 21000.0 nM\|= 49000.0 nM			NPASS
60 kDa heat shock protein, mitochondrial	Homo sapiens	P10809		11000 nM			BindingDB
60 kDa chaperonin	Escherichia coli (strain K12)	P0A6F5		> 250000.0 nM			NPASS
3-oxoacyl-acyl-carrier protein reductase	Plasmodium falciparum	Q965D6		= 2300.0 nM			NPASS
3-oxoacyl-acyl-carrier protein reductase	Plasmodium falciparum			2300 nM			BindingDB
3-hydroxyacyl-[acyl-carrier-protein] dehydratase	Plasmodium falciparum			8000 nM			BindingDB
Adenosine A3 receptor	Homo sapiens	P0DMS8				= 34000.0 nM	NPASS
Carbonic anhydrase 1	Homo sapiens	P00915				12800 nM	BindingDB
Gag-Pol polyprotein	HIV-1	P04585		2109.999895 nM			BindingDB
Carbonic anhydrase 3	Bovine	Q3SZX4				21300 nM	BindingDB
Carbonic anhydrase 2	Homo sapiens	P00918				4400 nM	BindingDB
Fatty acid synthase	Plasmodium falciparum	Q965D7		= 8000.0 nM			NPASS
Estrogen receptor beta	Human	Q92731		2927.175455 nM			BindingDB
Estrogen receptor beta	Homo sapiens	Q92731		= 2927.18 nM			NPASS
Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Q965D5		= 5000.0 nM			NPASS
Enoyl-acyl-carrier protein reductase	Plasmodium falciparum			5000 nM			BindingDB
Death-associated protein kinase 1	Homo sapiens	P53355		1600 nM\|11000 nM\|= 1600.0 nM\|= 11000.0 nM			BindingDB, NPASS
DNA-3-methyladenine glycosylase	Homo sapiens	P29372		2600 nM\|200000 nM\|100000 nM\|12000 nM\|= 2600.0 nM			BindingDB, NPASS
DNA topoisomerase II alpha	Homo sapiens	P11388		= 40.8 ug.mL-1			NPASS
Dipeptidyl peptidase 3	Homo sapiens	Q9NY33		8.50e+4 nM			BindingDB
DNA ligase 1	Homo sapiens	P18858		224000 nM\|= 68.0 ug.mL-1			BindingDB, NPASS
Carbonic anhydrase 4	Homo sapiens	P22748				15700 nM	BindingDB
DNA topoisomerase 2-alpha	Homo sapiens	P11388		135000 nM			BindingDB
Casein kinase 2	Rattus norvegicus			= 10000.0 nM			NPASS
Casein kinase II	Homo sapiens	P19784		= 10000.0 nM			NPASS
Casein kinase 2	Homo sapiens			= 10000.0 nM			NPASS
Chaperonin GroEL	Escherichia coli			>250000 nM			BindingDB
Co-chaperonin GroES	Escherichia coli			5200 nM\|8500 nM			BindingDB
Casein kinase II subunit alpha 3	Homo sapiens	Q8NEV1		10000 nM			BindingDB

a curated database

IMPPAT Phytochemical information:
Morin

Bioactivity information

IMPPAT Phytochemical information: Morin

Bioactivity information

IMPPAT Phytochemical information:
Morin