IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

Bioactivity information

Target name	Target organism	UniProt identifier	IC50	Kd	Ki	Source
SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2		> 20000.0 nM\|> 19952.62 nM			NPASS
Serotonin 1 (5-HT1) receptor	Rattus norvegicus	P28565		= 38.9 nM		NPASS
Serotonin 1a (5-HT1a) receptor	Homo sapiens	P08908		= 3.162 nM		NPASS
Serotonin 1a (5-HT1a) receptor	Rattus norvegicus	P19327			= 259.0 nM\|= 25.12 nM	NPASS
Serotonin 1b (5-HT1b) receptor	Rattus norvegicus	P28564			= 910.0 nM	NPASS
Serotonin transporter	Homo sapiens	P31645	= 1200.0 nM			NPASS
Serotonin 2 (5-HT2) receptor	Rattus norvegicus	P14842			= 380.0 nM	NPASS
Serotonin 2c (5-HT2c) receptor	Homo sapiens	P28335			= 70.0 nM	NPASS
Serotonin 7 (5-HT7) receptor	Rattus norvegicus	P32305			= 7.943 nM	NPASS
Sodium-dependent serotonin transporter	Homo sapiens	P31645	1200 nM			BindingDB
Rattus norvegicus	Rattus norvegicus		= 1318.26 nM\|= 12589.25 nM		= 341.0 nM\|= 6295.0 nM	NPASS
Serotonin 2 (5-HT2) receptor	Rattus norvegicus	P08909\|P14842\|P30994			380 nM	BindingDB
GABA-A receptor; anion channel	Rattus norvegicus	Q9ES14			> 100000.0 nM	NPASS
5-hydroxytryptamine receptor 2C	Homo sapiens	P28335			70 nM	BindingDB
5-hydroxytryptamine receptor 7	Rattus norvegicus	P32305			7.9 nM	BindingDB
5-hydroxytryptamine receptor 7	Cavia porcellus	P50407			19.95 nM\|95.49 nM\|21.37 nM	BindingDB
5-hydroxytryptamine receptor 6	Rattus norvegicus	P31388			4.46 nM\|112.2 nM	BindingDB
5-hydroxytryptamine receptor 6	Mus musculus	Q9R1C8			100 nM	BindingDB
5-hydroxytryptamine receptor 5B	Mus musculus	P31387			1584.89 nM	BindingDB
5-hydroxytryptamine receptor 5A	Mus musculus	P30966			1000 nM\|2900 nM	BindingDB
Acetylcholinesterase	Electrophorus electricus	O42275	11400 nM\|= 11400.0 nM			BindingDB, NPASS
5-hydroxytryptamine receptor 2A	Rattus norvegicus	P14842			404 nM\|182 nM\|68 nM	BindingDB
5-hydroxytryptamine receptor 2A	Homo sapiens	P28223			15 nM\|145 nM	BindingDB
5-hydroxytryptamine receptor 1F	Mus musculus	Q02284			31.62 nM	BindingDB
5-hydroxytryptamine receptor 1B	Rattus norvegicus	P28564			910 nM	BindingDB
5-hydroxytryptamine receptor 1A	Rattus norvegicus	P19327			21.38 nM\|1023.29 nM\|259 nM\|25 nM	BindingDB

a curated database

IMPPAT Phytochemical information:
Bufotenine

Bioactivity information

IMPPAT Phytochemical information: Bufotenine

Bioactivity information

IMPPAT Phytochemical information:
Bufotenine