IMPPAT Phytochemical information: 
6,11-dihydroxy-3,3-dimethyl-12H-pyrano[2,3-c]acridin-7-one
6,11-dihydroxy-3,3-dimethyl-12H-pyrano[2,3-c]acridin-7-one
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Glycogen synthase kinase-3Homo sapiensP49841> 10000.0 nMNPASS
Dual-specificity tyrosine-phosphorylation regulated kinase 1AHomo sapiensQ13627= 2200.0 nMNPASS
TGBC11TKBHomo sapiens= 2830.0 nMNPASS
HepG2Homo sapiens= 7300.0 nMNPASS
Dual specificty protein kinase CLK1Homo sapiensP49759>= 10000.0 nMNPASS
B16Mus musculus= 5580.0 nMNPASS
Cyclin-dependent kinase 5Homo sapiensQ00535>10000 nM|> 10000.0 nMBindingDB, NPASS
Cyclin-dependent kinase 1Homo sapiensP06493>10000 nM|> 10000.0 nMBindingDB, NPASS
CCRF-HSB-2Homo sapiens= 4650.0 nMNPASS
A549Homo sapiens= 6980.0 nM|= 7800.0 nMNPASS
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiensQ136272200 nMBindingDB