IMPPAT Phytochemical information: 
Digitoxigenin
Digitoxigenin
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
VeroChlorocebus aethiops< 50.0 nMNPASS
UACC-62Homo sapiens= 348.8 nMNPASS
TK-10Homo sapiens= 76.5 nMNPASS
T47DHomo sapiens= 2530.0 nMNPASS
Sodium/potassium-transporting ATPase subunit alpha-1Canis lupus familiarisP50997500 nMBindingDB
Sodium/potassium-transporting ATPase alpha-1 chainCanis lupus familiarisP50997= 500.0 nMNPASS
Sodium/potassium-transporting ATPaseHomo sapiensP54710= 500.0 nM|= 63.0 nM|= 250.0 nM|= 8.0 nM|= 120.0 nM|= 20.0 nMNPASS
SK-BR-3Homo sapiens= 4420.0 nMNPASS
Potassium-transporting ATPase alpha chain 2Homo sapiensP5470780 nM|= 80.0 nMBindingDB, NPASS
PC-3Homo sapiens= 2410.0 nMNPASS
NON-PROTEIN TARGET= 8950.0 nMNPASS
NCI-H460Homo sapiens= 920.0 nMNPASS
NCI-H187Homo sapiens= 9770.0 nMNPASS
WI-38 VA13Homo sapiens= 1900000.0 nMNPASS
MRC5Homo sapiens= 1160.0 nMNPASS
Monoclonal antibody (mAb)= 1000.0 nM|= 880.0 nMNPASS
A549Homo sapiens= 620.0 nM|> 316000.0 nM|= 0.24 ug.mL-1|= 1680.0 nMNPASS
Bcl-2-like protein 11Homo sapiensO43521>350000 nMBindingDB
HCT-8Homo sapiens= 2480.0 nMNPASS
HT-1080Homo sapiens= 1500.0 nMNPASS
Cavia porcellusCavia porcellus= 570.0 nM|= 600.0 nM|= 57.0 nMNPASS
Hs-578THomo sapiens= 1022.0 nM|= 92300.0 nMNPASS
KBHomo sapiens= 9610.0 nMNPASS
LNCaPHomo sapiens= 3700.0 nMNPASS
MCF7Homo sapiens= 1.69 ug.mL-1|= 194.4 nM|= 600.0 nM|= 9100.0 nMNPASS
MDA-MB-231Homo sapiens= 1.9 ug.mL-1NPASS
HepG2Homo sapiens= 18000000.0 nM|= 0.12 ug.mL-1NPASS