IMPPAT Phytochemical information: 
Silibinin
Silibinin
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Solute carrier family 2, facilitated glucose transporter member 4Mus musculusP14142= 60000.0 nMNPASS
SARS-CoV-2Severe acute respiratory syndrome coronavirus 2> 20000.0 nM|> 19952.62 nMNPASS
Solute carrier organic anion transporter family member 1B1Homo sapiensQ9Y6L6= 9700.0 nMNPASS
No relevant target= 360000.0 nMNPASS
Solute carrier organic anion transporter family member 2B1Homo sapiensO94956= 4500.0 nMNPASS
dengue virus type 3dengue virus type 3= 18480.0 nMNPASS
Solute carrier organic anion transporter family member 1B3Homo sapiensQ9NPD5= 2700.0 nMNPASS
NON-PROTEIN TARGET= 80000.0 nM|= 110000.0 nM|= 20000.0 nM|= 50000.0 nM|= 100000.0 nMNPASS
MCF7Homo sapiens= 222800.0 nMNPASS
HepatocyteMus musculus= 29900.0 nM|= 33600.0 nM|= 38800.0 nMNPASS
Hepatitis C virusHepatitis C virus= 50000.0 nMNPASS
HepG2Homo sapiens= 75700.0 nMNPASS
Heat shock protein HSP90Homo sapiensP08238= 500000.0 nMNPASS
HUVECHomo sapiens= 62330.0 nM|= 8830.0 nMNPASS
Cytochrome P450 3A4Homo sapiensP08684132000 nM|32000 nMBindingDB
Cytochrome P450 2C9Homo sapiensP11712= 18000.0 nM5000 nMBindingDB, NPASS