IMPPAT Phytochemical information: 
Theophylline
Theophylline
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
P2Y purinoceptor 2Cricetulus griseusP588254550 nMBindingDB
Chitotriosidase-1Homo sapiensQ13231>500000 nMBindingDB
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1ABos taurusP14100500000 nMBindingDB
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1CHomo sapiensP54750|Q01064|Q14123320000 nMBindingDB
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BBos taurusQ0106192000 nMBindingDB
Endochitinase B1Aspergillus fumigatusQ873X91500000 nMBindingDB
Intestinal-type alkaline phosphataseHomo sapiensP09923>5000 nMBindingDB
Palmitoleoyl-protein carboxylesterase NOTUMHomo sapiensQ6P9887000000 nMBindingDB
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3BHomo sapiensQ13370|Q14432360000 nMBindingDB
PhosphodiesteraseBos taurus77000 nMBindingDB
Phospholipase A-2-activating proteinHomo sapiensQ9Y263>5000 nMBindingDB
Replicase polyprotein 1abHuman SARS coronavirusP0C6X7100000 nMBindingDB
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiensP27815386000 nMBindingDB
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4DHomo sapiensP27815|Q07343|Q08493|Q084991780000 nM56800 nMBindingDB
cAMP-specific 3',5'-cyclic phosphodiesterase 4CRattus norvegicusP14644523000 nMBindingDB
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiensO00408210000 nMBindingDB
Bile salt export pumpHomo sapiensO95342>133000 nMBindingDB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformHomo sapiensP487362904000 nMBindingDB
Alkaline phosphatase, tissue-nonspecific isozymeHomo sapiensP05186>5000 nM82000 nMBindingDB
Adenosine receptor A3Homo sapiensP0DMS8>10000 nM|86000 nM|14 nM|22300 nM|85100 nM|52300 nMBindingDB
Adenosine receptor A3Ovis ariesP353429050 nMBindingDB
ATP-binding cassette sub-family C member 2Homo sapiensQ92887>133000 nMBindingDB
ATP-binding cassette sub-family C member 3Homo sapiensO15438>133000 nMBindingDB
Adenosine receptor A3Rattus norvegicusP28647100000 nM|85000 nMBindingDB
Adenosine receptor A1Bos taurusP281902430 nM|12700 nM6330 nM|>10000 nM|3800 nM|5300 nM|8500 nM|20000 nM|6000 nMBindingDB
Adenosine receptor A1Cavia porcellusP477455980 nM|7060 nM|9800 nM|23000 nM|13000 nMBindingDB
Adenosine receptor A1Homo sapiensP3054212000 nM6200 nM|0.6 nM|6920 nM|10100 nM|8500 nM|6770 nMBindingDB
Adenosine receptor A1Oryctolagus cuniculusP349704710 nMBindingDB
Adenosine receptor A1Rattus norvegicusP25099>10000 nM|20000 nM|28000 nM|19000 nM5600 nM|>10000 nM|9500 nM|8470 nM|13000 nM|14000 nM|8500 nM|7400 nM|17000 nM|26000 nM|6920 nM|700 nM|9200 nMBindingDB
ATP-binding cassette sub-family C member 4Homo sapiensO15439131000 nMBindingDB
Adenosine receptor A2aCavia porcellusP4661616600 nM|14000 nM|13000 nMBindingDB
Adenosine receptor A2aHomo sapiensP2927428200 nM3630 nM>10000 nM|1710 nM|4200 nM|25000 nM|21000 nM|0.6 nM|7900 nM|6700 nM|18500 nMBindingDB
Adenosine receptor A2aRattus norvegicusP3054319000 nM|25000 nM|8000 nM|9400 nM|22000 nM|6700 nMBindingDB
Adenosine receptor A2a/A2bHomo sapiensP29274|P2927513800 nM|14000 nM|16600 nMBindingDB
Adenosine receptor A2a/A2bRattus norvegicusP29276|P30543>10000 nM25300 nM|17000 nM|4800 nM|25000 nM|1310 nM|16000 nM|22000 nMBindingDB
Adenosine receptor A2bHomo sapiensP292757850 nM|9200 nM|9070 nM|7059.0 nM|2700 nMBindingDB
Adenosine receptor A2bRattus norvegicusP2927615100 nMBindingDB
Adenosine receptor A1/A2a/A2b/A3Rattus norvegicusP25099|P28647|P29276|P3054322000 nM|2000 nM|9000 nM|4500 nM|20000 nMBindingDB