IMPPAT Phytochemical information: 
Costunolide
Costunolide
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Pyruvate kinase isozymes M1/M2Homo sapiensP14618= 1513.0 nMNPASS
UDP-N-acetylglucosamine 1-carboxyvinyltransferaseEscherichia coli K-12P0A749> 50000.0 nMNPASS
UDP-N-acetylglucosamine 1-carboxyvinyltransferaseEscherichia coli (strain K12)P0A749>50000 nMBindingDB
Transcriptional activator MybGallus gallusP0110330690 nM|30660 nM|= 30690.22 nM|= 30660.0 nMBindingDB, NPASS
Telomerase reverse transcriptaseHomo sapiensO14746= 65000.0 nMNPASS
T-cell= 2570.0 nMNPASS
SW-620Homo sapiens= 7800.0 nMNPASS
RAW264.7Mus musculus> 50000.0 nMNPASS
PA-1Homo sapiens= 10600.0 nMNPASS
UDP-N-acetylglucosamine 1-carboxyvinyltransferasePseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)Q9HVW7>50000 nMBindingDB
NIH3T3Mus musculus= 13900.0 nMNPASS
MIA PaCa-2Homo sapiens= 17700.0 nMNPASS
KBHomo sapiens= 28900.0 nMNPASS
K562Homo sapiens= 14500.0 nMNPASS
HL-60Homo sapiens= 7700.0 nM|= 2100.0 nM|= 5900.0 nMNPASS
HBL-100Homo sapiens= 10300.0 nMNPASS
DU-145Homo sapiens= 29200.0 nMNPASS
C6Rattus norvegicus= 4100.0 nMNPASS
A549Homo sapiens= 12300.0 nMNPASS
NON-PROTEIN TARGET= 5800.0 nM|= 1.2 ug.mL-1|= 4100.0 nMNPASS
UDP-N-acetylglucosamine 1-carboxyvinyltransferasePseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)Q9HVW7> 50000.0 nMNPASS