IMPPAT Phytochemical information: 
Diphyllin
Diphyllin
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
MIA PaCa-2Homo sapiens= 271.0 nMNPASS
MONO-MAC-6Homo sapiens= 3900.0 nMNPASS
NCI-H838Homo sapiens= 16000.0 nMNPASS
Nuclear receptor subfamily 0 group B member 1Homo sapiensP51843>67554 nM|> 67554.0 nMBindingDB, NPASS
Orotidine 5'-phosphate decarboxylaseAspergillus nigerP07817>59660 nMBindingDB
PC-3Homo sapiens= 7200.0 nM|= 3800.0 nMNPASS
PaTu 8988tHomo sapiens= 102.0 nMNPASS
Steroidogenic factor 1Homo sapiensQ13285>67554 nMBindingDB
Platelet> 100000.0 nMNPASS
SARS-CoV-2Severe acute respiratory syndrome coronavirus 2= 1920.0 nM|> 100000.0 nMNPASS
SW480Homo sapiens= 3400.0 nMNPASS
TE-1Homo sapiens= 280.0 nMNPASS
Vero C1008Chlorocebus sabaeus> 100000.0 nMNPASS
n.a.> 67554.0 nMNPASS
MCF7Homo sapiens= 540.0 nMNPASS
Panc02Mus musculus= 61.0 nMNPASS
LeishmaniaLeishma= 14400.0 nMNPASS
Glycogen synthase kinase-3 betaHomo sapiensP498414421 nMBindingDB
L02Homo sapiens= 3322.0 nMNPASS
A2058Homo sapiens= 2600.0 nMNPASS
A549Homo sapiens= 8000.0 nM|= 2020.0 nM|= 24010.0 nM|= 8800.0 nMNPASS
ATP-dependent molecular chaperone HSP82Candida albicans (strain WO-1) (Yeast)C4YTQ8= 2212.0 nMNPASS
CFPAC-1Homo sapiens= 208.0 nMNPASS
Calu-1Homo sapiens= 31800.0 nMNPASS
EBC-1Homo sapiens= 14800.0 nMNPASS
ECa-109 cell lineHomo sapiens= 210.0 nMNPASS
LNCaPHomo sapiens= 11500.0 nMNPASS
HCT-116Homo sapiens= 3540.0 nM|= 48500.0 nMNPASS
HEK293Homo sapiens> 59660.0 nM= 774400.0 nM|> 100000.0 nMNPASS
HT-29Homo sapiens= 7600.0 nM|= 19500.0 nMNPASS
HepG2Homo sapiens> 500000.0 nM|= 21600.0 nMNPASS
Human immunodeficiency virus 1Human immunodeficiency virus 1= 1710.0 nMNPASS
K562Homo sapiens= 1670.0 nM|= 23460.0 nM|= 2380.0 nMNPASS
KBHomo sapiens= 780.0 nM|= 3150.0 nM|= 5300.0 nMNPASS