IMPPAT Phytochemical information: 
(S)-Tetrahydrocolumbamine
(S)-Tetrahydrocolumbamine
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Dopamine D5 receptorHomo sapiensP21918= 9.5 nMNPASS
Dopamine D4 receptorHomo sapiensP21917= 77.4 nMNPASS
Dopamine D3 receptorHomo sapiensP35462= 37.3 nMNPASS
Dopamine D2 receptorHomo sapiensP14416= 91.0 nM|= 41.8 nMNPASS
Dopamine D1 receptorHomo sapiensP21728= 4.5 nM|= 6.2 nMNPASS
Sigma non-opioid intracellular receptor 1Homo sapiensQ99720106 nMBindingDB
D(3) dopamine receptorHomo sapiensP3546237 nMBindingDB
D(2) dopamine receptorHomo sapiensP14416102 nM|42 nM|91 nMBindingDB
D(1B) dopamine receptorHomo sapiensP219189.5 nMBindingDB
D(1A) dopamine receptorHomo sapiensP2172815 nM|6.2 nM|4.5 nMBindingDB
D(4) dopamine receptorHomo sapiensP2191777 nMBindingDB