| Target name | Target organism | UniProt identifier | EC50 | IC50 | Kd | Ki | Source |
|---|
| Catalase | Rattus norvegicus | P04762 | 17600 nM|= 5.06 ug.mL-1 | | | | BindingDB, NPASS |
| Cholinesterase | Equus caballus | P81908 | | 19340 nM|12700 nM|16900 nM|8500 nM|17380 nM|28300 nM|14400 nM|22390 nM|15800 nM|46030 nM|11900 nM|18130 nM|15700 nM|8404 nM|1520 nM|3200 nM|8400 nM|12600 nM|12000 nM|15240 nM|21850 nM|24400 nM|40720 nM|7960 nM|39030 nM|3310 nM|9400 nM|14920 nM|19780 nM|28100 nM|40830 nM|24410 nM|16320 nM|3900 nM|7900 nM|5470 nM|= 14400.0 nM|= 15700.0 nM|= 24400.0 nM|= 8400.0 nM|= 8394.6 nM|= 8404.0 nM|= 12000.0 nM|= 3200.0 nM|= 12600.0 nM|= 7960.0 nM|= 19340.0 nM|= 12700.0 nM|= 39030.0 nM|= 13610.0 nM|= 17380.0 nM|= 19780.0 nM|= 28100.0 nM|= 28300.0 nM|= 22390.0 nM|= 15800.0 nM|= 46030.0 nM|= 11900.0 nM|= 18130.0 nM|= 21850.0 nM|= 40720.0 nM|= 3310.0 nM|= 9400.0 nM|= 24410.0 nM|= 16320.0 nM|= 3900.0 nM|= 11680.0 nM|= 5470.0 nM|= 7900.0 nM|= 16076.0 nM | | 9370 nM|2070 nM|4240 nM|21500 nM|7700 nM|= 7700.0 nM | BindingDB, NPASS |
| Cholinesterase | Homo sapiens | P06276 | | 7300 nM|>10000 nM|8.5e+3 nM|6.65e+4 nM|40830 nM|8000 nM|21900 nM|18000 nM|12700 nM|1320 nM|8400 nM|8500 nM|19340 nM|50900 nM|10000 nM|18600 nM|>50000 nM|1200 nM|19100 nM|20700 nM|18600000 nM|3720 nM|19270 nM|7000 nM|2000 nM|170 nM|15800 nM|13180 nM|42300 nM|575 nM|16500 nM|9400000 nM|42000 nM|31600 nM|13700 nM|10600 nM|29310 nM|19710 nM|2015 nM | | 21500 nM|193 nM|28290 nM|192 nM | BindingDB |
| Cholinesterase | Human | P06276 | | 21900 nM | | | BindingDB |
| G-361 | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| Glutamate [NMDA] receptor subunit epsilon 2 | Rattus norvegicus | Q00960 | | | | > 100000.0 nM | NPASS |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus | Q00960 | | | | >100000 nM | BindingDB |
| HeLa | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| HepG2 | Homo sapiens | | | = 4200000.0 nM | | | NPASS |
| MCF7 | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| Leishmania donovani | Leishmadonovani | | | > 30.0 ug.mL-1 | | | NPASS |
| Carboxylic ester hydrolase | Horse | | | 1.50e+4 nM|2770 nM|15000 nM|2.325e+4 nM | | | BindingDB |
| Multidrug resistance-associated protein 4 | Homo sapiens | O15439 | | > 133000.0 nM | | | NPASS |
| NON-PROTEIN TARGET | | | = 2810.0 nM|= 1940.0 nM|= 1480.0 nM | | | | NPASS |
| Plasmodium falciparum (isolate K1 / Thailand) | Plasmodium falciparum K1 | | | = 4.38 ug.mL-1 | | | NPASS |
| Prolyl endopeptidase | Homo sapiens | P48147 | | >200000 nM|> 200000.0 nM | | | BindingDB, NPASS |
| SARS-CoV-2 | Severe acute respiratory syndrome coronavirus 2 | | | > 20000.0 nM|> 19952.62 nM | | | NPASS |
| SH-SY5Y | Homo sapiens | | | = 747.0 nM|= 4700000.0 nM | | | NPASS |
| Trypanosoma brucei rhodesiense | Trypanosoma brucei rhodesiense | | | > 30.0 ug.mL-1 | | | NPASS |
| Trypanosoma cruzi | Trypanosoma cruzi | | | > 30.0 ug.mL-1 | | | NPASS |
| K562 | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| Carboxylic ester hydrolase | Equus caballus | | | 7.96e+3 nM|1.738e+4 nM|6.19e+4 nM|1.5e+4 nM|8.8e+3 nM|8500 nM|8400 nM|15240 nM|15700 nM|12600 nM|14400 nM | | 3.2e+4 nM|8000 nM | BindingDB |
| Carboxylic ester hydrolase | Rattus norvegicus | | | 5900 nM | | | BindingDB |
| Acetylcholinesterase | Bos taurus | P23795 | | 8700 nM|= 8700.0 nM | | | BindingDB, NPASS |
| ATP-binding cassette sub-family C member 2 | Homo sapiens | Q92887 | | >133000 nM | | | BindingDB |
| ATP-binding cassette sub-family C member 3 | Homo sapiens | O15438 | | >133000 nM | | | BindingDB |
| ATP-binding cassette sub-family C member 4 | Homo sapiens | O15439 | | >133000 nM | | | BindingDB |
| Acetylcholine receptor protein epsilon chain | Homo sapiens | Q04844 | | = 0.767 ug.mL-1 | | | NPASS |
| Acetylcholine receptor subunit epsilon | Homo sapiens | Q04844 | | 2660 nM | | | BindingDB |
| Canalicular multispecific organic anion transporter 2 | Homo sapiens | O15438 | | > 133000.0 nM | | | NPASS |
| Acetylcholinesterase | Electrophorus electricus | O42275 | | 614 nM|360 nM|4e+3 nM|2.41e+3 nM|665 nM|3.5e+3 nM|5.4e+2 nM|4.0e+3 nM|1540 nM|4000 nM|4e+2 nM|5.3e+2 nM|500 nM|2090 nM|2670 nM|35000 nM|2200 nM|640 nM|3180 nM|2410 nM|1820 nM|550 nM|480 nM|3120 nM|12730 nM|610 nM|4480 nM|560 nM|2050 nM|623 nM|636 nM|670 nM|1020 nM|3570 nM|8000 nM|3200 nM|2800 nM|2000 nM|600 nM|21820 nM|250 nM|1450 nM|7440 nM|4420 nM|2400 nM|10530 nM|1670 nM|1700 nM|1230 nM|1560 nM|8500 nM|3250 nM|3580 nM|1280 nM|3560 nM|2700 nM|150 nM|1290 nM|= 35000.0 nM|= 360.0 nM|= 2200.0 nM|= 500.0 nM|= 640.0 nM|= 635.33 nM|= 3180.0 nM|= 550.0 nM|= 1820.0 nM|= 3200.0 nM|= 623.0 nM|= 636.0 nM|= 560.0 nM|= 2000.0 nM|= 600.0 nM|= 7440.0 nM|= 4000.0 nM|= 1450.0 nM|= 2090.0 nM|= 2670.0 nM|= 2400.0 nM|= 10530.0 nM|= 2770.0 nM|= 2410.0 nM|= 665.0 nM|= 8500.0 nM|= 0.45 ug.mL-1|= 480.0 nM|= 3120.0 nM|= 12730.0 nM|= 610.0 nM|= 4480.0 nM|= 2050.0 nM|= 1020.0 nM|= 3570.0 nM|= 8000.0 nM|= 2800.0 nM|= 21820.0 nM|= 250.0 nM|= 1670.0 nM|= 1700.0 nM|= 3580.0 nM|= 1280.0 nM|= 3560.0 nM|= 1290.0 nM|= 150.0 nM|= 1000.0 nM|= 1650.0 nM|= 132.0 nM|= 2700.0 nM | | 540 nM|440 nM|1560 nM|428 nM|400 nM|450 nM|1060 nM|370 nM|3000 nM|= 1560.0 nM|= 440.0 nM|= 428.0 nM|= 1060.0 nM|= 3000.0 nM|= 500.0 nM | BindingDB, NPASS |
| Acetylcholinesterase | Homo sapiens | P22303 | 1100 nM|= 1100.0 nM | 800 nM|2.6e+3 nM|1100 nM|550 nM|980 nM|700 nM|2000 nM|2670 nM|3200 nM|600 nM|90000 nM|500 nM|350 nM|2010 nM|2090 nM|300 nM|73900 nM|1300 nM|530 nM|3800 nM|7300 nM|2600 nM|100 nM|355 nM|590 nM|1070 nM|1180 nM|2100 nM|1000 nM|1270 nM|1900 nM|13900 nM|1600 nM|1700 nM|3030 nM|2770 nM|17100 nM|6400 nM|3000 nM|790 nM|2900 nM|1720000 nM|8400 nM|1170 nM|= 800.0 nM|= 100.0 nM|~ 500.0 nM|= 590.0 nM|= 600.0 nM|= 635.33 nM|= 3200.0 nM|= 2010.0 nM|= 1070.0 nM|= 980.0 nM|= 500.0 nM|= 350.0 nM|= 1180.0 nM|= 73900.0 nM|= 2100.0 nM|= 530.0 nM|= 2600.0 nM|= 7300.0 nM|= 1156.0 nM|= 300.0 nM|= 1000.0 nM|= 2090.0 nM|= 2000.0 nM|= 550.0 nM|= 1100.0 nM|= 2670.0 nM|= 700.0 nM|= 90000.0 nM|= 1300.0 nM|= 355.0 nM|= 1270.0 nM|= 1900.0 nM|= 13900.0 nM|= 1600.0 nM|= 1700.0 nM|= 3800.0 nM|= 3030.0 nM|= 2770.0 nM|= 17100.0 nM|= 6400.0 nM|= 3000.0 nM|= 790.0 nM|= 1200.0 nM|= 1170.0 nM|= 8400.0 nM|= 594.0 nM|= 1725000.0 nM|= 1290.0 nM|= 2900.0 nM | | 62 nM|250 nM|300 nM|= 300.0 nM|= 61.96 nM|= 61.9 nM|= 250.0 nM|= 500.0 nM|= 540.0 nM | BindingDB, NPASS |
| Acetylcholinesterase | Human | P22303 | | 700 nM | | | BindingDB |
| Acetylcholinesterase | Mus musculus | P21836 | | 2080 nM|2500 nM|= 2500.0 nM|= 2080.0 nM | | | BindingDB, NPASS |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens | Q92887 | | > 133000.0 nM | | | NPASS |
| Acetylcholinesterase | Tetronarce californica | P04058 | | 418 nM|360 nM|550 nM|1069 nM|652 nM|590 nM | | 1.9e+2 nM | BindingDB |
| Acetylcholinesterase | Rattus norvegicus | P37136 | | 538 nM|750 nM|1165 nM|1030000 nM|1760 nM|630 nM|920 nM|2550 nM|= 1030000.0 nM|= 538.0 nM|= 750.0 nM|= 630.0 nM|= 1760.0 nM|= 1165.0 nM|= 920.0 nM|= 2550.0 nM | | | BindingDB, NPASS |
| Butyrylcholinesterase | Rattus norvegicus | Q9JKC1 | | = 5900.0 nM | | | NPASS |
| Butyrylcholinesterase | Homo sapiens | P06276 | | = 18000.0 nM|= 7300.0 nM|= 8400.0 nM|= 8394.6 nM|= 20700.0 nM|> 10000.0 nM|= 8500.0 nM|= 18600000.0 nM|= 8000.0 nM|= 50900.0 nM|= 18600.0 nM|= 170.0 nM|= 7000.0 nM|= 10000.0 nM|= 15800.0 nM|= 12700.0 nM|= 21900.0 nM|= 0.38 ug.mL-1|= 6.34 ug.mL-1|= 66500.0 nM|= 1200.0 nM|= 19100.0 nM|= 3720.0 nM|= 2000.0 nM|= 13180.0 nM|= 42300.0 nM|= 575.0 nM|= 16500.0 nM|= 9400000.0 nM|= 19340.0 nM|= 42000.0 nM|= 31600.0 nM|= 13700.0 nM|= 15600.0 nM|= 2015.0 nM|= 10010.0 nM|= 34000.0 nM|= 19710.0 nM|= 10600.0 nM|= 29310.0 nM|= 19270.0 nM | | = 192.47 nM|= 192.5 nM|= 28290.0 nM|= 9400.0 nM|= 9370.0 nM | NPASS |
| Butyrylcholinesterase | Equus caballus | Q9N1N9 | | = 8500.0 nM|= 8400.0 nM|= 15240.0 nM|= 14400.0 nM|= 8394.6 nM|= 15700.0 nM | | = 8000.0 nM | NPASS |
| CCRF-CEM | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| Bile salt export pump | Homo sapiens | O95342 | | >135000 nM|>133000 nM|> 135000.0 nM|> 133000.0 nM | | | BindingDB, NPASS |
| BJ | Homo sapiens | | | > 50000.0 nM | | | NPASS |
| Acetylcholinesterase | Torpedo californica | P04058 | | = 360.0 nM|= 550.0 nM|= 652.0 nM|= 590.0 nM | | | NPASS |
| Brain | Rattus norvegicus | | = 4.93 ug.mL-1|= 4.21 ug.mL-1 | | | | NPASS |
