IMPPAT Phytochemical information: 
Bisdemethoxycurcumin
Bisdemethoxycurcumin
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
MDA-MB-231Homo sapiens= 21900.0 nM|= 38500.0 nM|= 24000.0 nM|= 11000000.0 nMNPASS
MCF7Homo sapiens= 24300.0 nM|= 33780.0 nM|= 48900.0 nMNPASS
Monoamine oxidase BHomo sapiensP27338= 2590.0 nM= 800.0 nMNPASS
Leishmania majorLeishmamajor= 72000.0 nMNPASS
Leishmania mexicanaLeishmamexicana= 63000.0 nMNPASS
Multidrug resistance protein CDR1Candida albicansP43071= 40000.0 nMNPASS
WRL68Homo sapiens= 45400.0 nMNPASS
NON-PROTEIN TARGET= 22300.0 nM|> 100000.0 nM|= 91400.0 nM|= 54300.0 nM|> 25000.0 nMNPASS
PC-3Homo sapiens= 27300.0 nMNPASS
Radical scavenging activity> 100000.0 nMNPASS
Sortase AStaphylococcus aureusQ9S446= 103500.0 nMNPASS
Trypanosoma brucei bruceiTrypanosoma brucei brucei= 7700.0 nM|= 9500.0 nM|= 4500.0 nMNPASS
LNCaPHomo sapiens= 19700.0 nMNPASS
NCI-H460Homo sapiens= 88100.0 nMNPASS
KBHomo sapiens= 21440.0 nMNPASS
A-431Homo sapiens> 100000.0 nMNPASS
HepG2Homo sapiens> 50000.0 nM|= 62900.0 nM|= 75500.0 nMNPASS
HT-1080Homo sapiens= 7000.0 nMNPASS
HL-60Homo sapiens= 25120.0 nMNPASS
HEK293Homo sapiens= 200000.0 nMNPASS
Glyoxalase IHomo sapiensQ04760= 18000.0 nM|= 18200.0 nMNPASS
DU-145Homo sapiens= 30100.0 nMNPASS
DLD-1Homo sapiens> 40000.0 nMNPASS
Cyclooxygenase-2Homo sapiensP35354= 36370.0 nMNPASS
CpG DNA methylaseSpiroplasma monobiaeP15840= 30.0 nMNPASS
CaM kinase II alphaHomo sapiensQ9UQM7= 37000.0 nMNPASS
Aldose reductaseHomo sapiensP15121= 5100.0 nMNPASS
Aldo-keto reductase family 1 member B10Homo sapiensO60218= 60.0 nMNPASS
AcetylcholinesteraseElectrophorus electricusO42275= 18270.0 nMNPASS
A549Homo sapiens= 38100.0 nMNPASS
Human immunodeficiency virus type 1 integraseHuman immunodeficiency virus 1Q7ZJM1= 120000.0 nM|= 80000.0 nM|> 100000.0 nM|= 100000.0 nMNPASS