IMPPAT Phytochemical information: 
12a-Hydroxyrotenone
12a-Hydroxyrotenone
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
U-937Homo sapiens= 3600.0 nM|= 70.0 nM|= 90.0 nMNPASS
RajiHomo sapiens= 2400.0 nM|= 5600.0 nMNPASS
NON-PROTEIN TARGET= 200.0 nMNPASS
NCI-H460Homo sapiens= 2000.0 nMNPASS
Human immunodeficiency virus type 1 reverse transcriptaseHuman immunodeficiency virus 1Q72547> 200.0 ug.mL-1NPASS
HT-29Homo sapiens= 100.0 nMNPASS
Reverse transcriptaseHuman immunodeficiency virus 1>487000 nMBindingDB
HCC 2998Homo sapiens= 2900.0 nMNPASS
697Homo sapiens= 700.0 nM|= 500.0 nMNPASS
A2780Homo sapiens= 0.5 ug.mL-1|= 950.0 nMNPASS
HCT-116Homo sapiens= 0.055 ugNPASS
DU-145Homo sapiens= 2700.0 nMNPASS
BT-549Homo sapiens= 1600.0 nMNPASS