IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

Bioactivity information

Target name	Target organism	UniProt identifier	IC50	Ki	Source
5-hydroxytryptamine receptor 5B	Mus musculus	P31387		3.16 nM	BindingDB
5-hydroxytryptamine receptor 5B	Rattus norvegicus	P35365		6.3 nM\|15.84 nM	BindingDB
5-hydroxytryptamine receptor 6	Mus musculus	Q9R1C8		50.11 nM	BindingDB
5-hydroxytryptamine receptor 6	Rattus norvegicus	P31388		107.15 nM\|2.34 nM	BindingDB
5-hydroxytryptamine receptor 7	Cavia porcellus	P50407		138.03 nM\|48.97 nM	BindingDB
5-hydroxytryptamine receptor 7	Mus musculus	P32304		50.11 nM	BindingDB
5-hydroxytryptamine receptor 7	Rattus norvegicus	P32305		16 nM\|17.37 nM\|17 nM	BindingDB
Gastrin/cholecystokinin type B receptor	Mus musculus	P56481	17000 nM		BindingDB
Alpha-1A adrenergic receptor	Rattus norvegicus	P43140		12 nM\|25 nM	BindingDB
ATP-dependent translocase ABCB1	Mus musculus	P21447		188800 nM	BindingDB
Adenylate cyclase	Arthrospira platensis		70000 nM		BindingDB
Alpha-2C adrenergic receptor	Rattus norvegicus	P22086		12 nM\|4 nM\|3.5 nM\|6.3 nM	BindingDB
Beta-2 adrenergic receptor	Homo sapiens	P07550		>10000 nM	BindingDB
Cholecystokinin receptor type A	Mus musculus	O08786	34000 nM		BindingDB
D(1A) dopamine receptor	Bos taurus	Q95136		30 nM	BindingDB
D(2) dopamine receptor	Bos taurus	P20288		1.8 nM	BindingDB
ATP-dependent translocase ABCB1	Mus musculus	P06795		18000 nM	BindingDB
5-hydroxytryptamine receptor 5A	Rattus norvegicus	P35364		15.7 nM\|6.3 nM	BindingDB
ATP-dependent translocase ABCB1	Homo sapiens	P08183		98900 nM\|14250 nM	BindingDB
5-hydroxytryptamine receptor 5A	Homo sapiens	P47898		22 nM\|14 nM\|40 nM	BindingDB
5-hydroxytryptamine receptor 5A	Mus musculus	P30966		3.98 nM\|6.3 nM\|38 nM	BindingDB
5-hydroxytryptamine 1D receptor	Bos taurus			0.9 nM	BindingDB
5-hydroxytryptamine receptor 1A	Rattus norvegicus	P19327		3 nM	BindingDB
5-hydroxytryptamine receptor 1B	Homo sapiens	P28222		2.1 nM	BindingDB
5-hydroxytryptamine receptor 1B	Rattus norvegicus	P28564		0.03 nM	BindingDB
5-hydroxytryptamine receptor 1D	Homo sapiens	P28221		0.8 nM\|6 nM\|4.3 nM	BindingDB
5-hydroxytryptamine receptor 1D	Rattus norvegicus	P28565		0.07 nM	BindingDB
5-hydroxytryptamine receptor 1E	Homo sapiens	P28566		599 nM\|155 nM\|602.55 nM\|575.43 nM\|537.03 nM	BindingDB
5-hydroxytryptamine receptor 1D	Canis lupus familiaris	P11614		1.94 nM	BindingDB
5-hydroxytryptamine receptor 1F	Homo sapiens	P30939		169.82 nM\|171 nM	BindingDB
5-hydroxytryptamine receptor 1E	Rattus norvegicus			600 nM	BindingDB
5-hydroxytryptamine receptor 2C	Homo sapiens	P28335		9.77 nM	BindingDB
5-hydroxytryptamine receptor 2B	Homo sapiens	P41595		3.54 nM\|3 nM	BindingDB
5-hydroxytryptamine receptor 2A	Rattus norvegicus	P14842		1.41 nM\|9 nM	BindingDB
5-hydroxytryptamine receptor 2C	Rattus norvegicus	P08909		2.45 nM\|12 nM	BindingDB
5-hydroxytryptamine receptor 1F	Rattus norvegicus	P30940		52.48 nM	BindingDB
5-hydroxytryptamine receptor 1F	Mus musculus	Q02284		50.11 nM	BindingDB
5-hydroxytryptamine receptor 2A	Homo sapiens	P28223		0.64 nM	BindingDB

a curated database

IMPPAT Phytochemical information:
Ergotamine

Bioactivity information

IMPPAT Phytochemical information: Ergotamine

Bioactivity information

IMPPAT Phytochemical information:
Ergotamine