IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

IMPPAT Phytochemical information:
Cytisine

Cytisine

Bioactivity information

Target name	Target organism	UniProt identifier	EC50	IC50	Kd	Ki	Source
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus	P09483				0.48 nM\|0.34 nM	BindingDB
Neuronal acetylcholine receptor subunit alpha-7	Rattus norvegicus	Q05941				331 nM\|1000 nM\|0.9 nM\|4200 nM\|5820 nM\|300 nM\|8000 nM\|230 nM\|261 nM\|1700 nM	BindingDB
Neuronal acetylcholine receptor subunit alpha-7	Homo sapiens	P36544	71000 nM			5890 nM\|4200 nM\|1420 nM	BindingDB
Neuronal acetylcholine receptor subunit alpha-4/beta-4	Rattus norvegicus	P09483\|P12392				2.2 nM\|2.1 nM	BindingDB
Neuronal acetylcholine receptor subunit alpha-4/beta-2	Rattus norvegicus	P09483\|P12390	8.8 nM	69 nM		1.5 nM\|1.06 nM\|1.53 nM\|4.2 nM\|0.123 nM\|1.9 nM\|0.122000 nM\|0.400000 nM	BindingDB
Neuronal acetylcholine receptor subunit alpha-4/beta-2	Homo sapiens	P17787\|P43681	38000 nM\|0.420000 nM			0.23 nM\|2.59 nM\|0.280000 nM	BindingDB
Neuronal acetylcholine receptor subunit alpha-3/beta-4	Rattus norvegicus	P04757\|P12392	25 nM			210 nM\|203 nM\|217 nM	BindingDB
Neuronal acetylcholine receptor subunit alpha-2/beta-2	Rattus norvegicus	P12389\|P12390				1.4 nM\|1.1 nM	BindingDB
Neuronal acetylcholine receptor subunit alpha-3/beta-2	Rattus norvegicus	P04757\|P12390				37 nM	BindingDB
Neuronal acetylcholine receptor subunit alpha-3/beta-2	Homo sapiens	P17787\|P32297	67000 nM				BindingDB
Neuronal acetylcholine receptor subunit alpha-2/beta-4	Rattus norvegicus	P12389\|P12392				5.4 nM	BindingDB
Acetylcholine receptor subunit delta	Tetronarce californica	P02718	10000 nM				BindingDB
Acetylcholine receptor subunit alpha/beta/delta/gamma	Tetronarce californica	P02710\|P02712\|P02714\|P02718				250 nM	BindingDB
Acetylcholine receptor subunit alpha/beta/delta/gamma	Homo sapiens	P02708\|P07510\|P11230\|Q07001	11 nM				BindingDB
Neuronal acetylcholine receptor subunit alpha-3/beta-4	Homo sapiens	P30926\|P32297	26000 nM				BindingDB