IMPPAT Phytochemical information: 
alpha-Lapachone
alpha-Lapachone
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
MCF7Homo sapiens= 38000.0 nM|> 30000.0 nMNPASS
MDA-MB-231Homo sapiens> 10000.0 nM|> 30000.0 nMNPASS
MRC5Homo sapiens> 100000.0 nMNPASS
NON-PROTEIN TARGET= 27700.0 nM|= 34300.0 nM|= 28700.0 nMNPASS
OVCAR-8Homo sapiens= 14790.0 nMNPASS
P388Mus musculus= 800.0 nMNPASS
Plasmodium falciparumPlasmodium falciparum> 50000.0 nM|= 15800.0 nMNPASS
SF-295Homo sapiens= 18770.0 nMNPASS
SK-MEL-2Homo sapiens= 7900.0 nMNPASS
SW626Homo sapiens= 12400.0 nMNPASS
Trypanosoma cruziTrypanosoma cruzi= 210.0 nM|> 4800000.0 nM|= 3190.0 nMNPASS
Lu1Homo sapiens= 21900.0 nMNPASS
PBMCHomo sapiens> 20660.0 nMNPASS
Leptomonas seymouriLeptomonas seymouri= 4100.0 nMNPASS
A549Homo sapiens> 30000.0 nMNPASS
Leishmania amazonensisLeishmaamazonensis= 15150.0 nM|= 16080.0 nMNPASS
Leishmania infantumLeishmaitum= 5850.0 nM|= 13880.0 nMNPASS
Col2Homo sapiens= 40900.0 nMNPASS
Crithidia fasciculataCrithidia fasciculata= 27000.0 nMNPASS
HL-60Homo sapiens= 13460.0 nM|= 8180.0 nMNPASS
HaCaTHomo sapiens= 10000.0 nMNPASS
HCT-116Homo sapiens= 19110.0 nMNPASS
Indoleamine 2,3-dioxygenase 1Homo sapiensP149024340 nMBindingDB
J774.A1Mus musculus= 285.0 ug.mL-1NPASS
K562Homo sapiens> 10000.0 nMNPASS
KBHomo sapiens= 53700.0 nMNPASS
LNCaPHomo sapiens= 29300.0 nMNPASS
Indoleamine 2,3-dioxygenaseHomo sapiensP14902= 4340.0 nMNPASS