IMPPAT Phytochemical information: 
gamma-Mangostin
gamma-Mangostin
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
MDA-MB-231Homo sapiens= 5870.0 nM|= 6600.0 nMNPASS
TransthyretinHomo sapiensP02766= 10000.0 nMNPASS
SW-620Homo sapiens= 5690.0 nMNPASS
SK-BR-3Homo sapiens= 25990.0 nMNPASS
RAW264.7Mus musculus> 50000.0 nMNPASS
Protein-tyrosine phosphatase 1BHomo sapiensP18031= 2800.0 nM= 2700.0 nMNPASS
Phosphoglycerate mutase 1Homo sapiensP18669= 1900.0 nMNPASS
NCI-H460Homo sapiens= 4480.0 nMNPASS
NCI-H1299Homo sapiens= 2200.0 nMNPASS
NAD-dependent deacetylase sirtuin 2Homo sapiensQ8IXJ6= 3800.0 nMNPASS
MCF7Homo sapiens> 10000.0 nMNPASS
SialidaseClostridium perfringensP10481= 2200.0 nM= 800.0 nM|= 7410.0 nMNPASS
HepG2Homo sapiens> 10000.0 nMNPASS
7,8-dihydro-8-oxoguanine triphosphataseHomo sapiensP36639= 2000.0 nMNPASS
ASPC1Homo sapiens= 5920.0 nMNPASS
Alpha glucosidaseHomo sapiens= 1700.0 nM= 1400.0 nMNPASS
Cyclooxygenase-1Homo sapiensP23219= 800.0 nMNPASS
Isocitrate dehydrogenase [NADP] cytoplasmicHomo sapiensO75874= 3170.0 nMNPASS
Cytochrome P450 19A1Homo sapiensP11511= 6900.0 nM|= 4970.0 nMNPASS
Fatty acid synthaseHomo sapiensP49327= 1240.0 nMNPASS
HL-60Homo sapiens= 6100.0 nMNPASS
HT-29Homo sapiens> 10000.0 nMNPASS
Cyclooxygenase-2Homo sapiensP35354= 2000.0 nMNPASS