IMPPAT Phytochemical information: 
Xanthohumol
Xanthohumol
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Nuclear factor NF-kappa-B complexHomo sapiensQ00653|P19838|Q04206> 30000.0 nMNPASS
PC-3Homo sapiens= 10670.0 nMNPASS
Plasmodium falciparumPlasmodium falciparum= 8200.0 nM|= 24000.0 nMNPASS
Protein kinase C alphaHomo sapiensP17252> 100000.0 nMNPASS
Protein kinase C thetaHomo sapiensQ04759> 100000.0 nMNPASS
Thioredoxin reductaseHomo sapiensQ86VQ6> 40000.0 nMNPASS
Radical scavenging activity= 1980.0 nMNPASS
SGC-7901Homo sapiens= 10000.0 nMNPASS
NON-PROTEIN TARGET= 15000.0 nM|= 11400.0 nM|= 1980.0 nMNPASS
TransthyretinHomo sapiensP02766= 12000.0 nMNPASS
VSMC= 3490.0 nMNPASS
RAW264.7Mus musculus= 8300.0 nMNPASS
NCI-H460Homo sapiens= 6900.0 nM|= 7500.0 nMNPASS
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2P0DTD116000 nMBindingDB
MCF7Homo sapiens= 10950.0 nM|= 3470.0 nM|= 13300.0 nMNPASS
Lymphocyte antigen 96Homo sapiensQ9Y6Y9= 460000.0 nMNPASS
IshikawaHomo sapiens= 4200.0 nMNPASS
Human immunodeficiency virus 1Human immunodeficiency virus 1= 1.28 ug.mL-1|= 0.5 ug.mL-1|= 20.74 ug.mL-1NPASS
HepG2Homo sapiens= 35000.0 nMNPASS
HeLaHomo sapiens= 9400.0 nM|= 40400.0 nMNPASS
HT-29Homo sapiens= 91310.0 nMNPASS
BV-2Mus musculus= 7920.0 nMNPASS
NCI-H1975Homo sapiens= 13000.0 nMNPASS
BGC-823Homo sapiens= 7800.0 nMNPASS
Arachidonate 5-lipoxygenaseHomo sapiensP09917= 2100.0 nM|= 2900.0 nMNPASS
A549Homo sapiens= 30500.0 nM|= 11900.0 nMNPASS
3-phosphoinositide dependent protein kinase-1Homo sapiensO15530= 6600.0 nMNPASS