IMPPAT Phytochemical information: 
2-Hydroxy-1,4-naphthaquinone
2-Hydroxy-1,4-naphthaquinone
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Tyrosine-protein phosphatase non-receptor type 22Homo sapiensQ9Y2R25600 nMBindingDB
MDA-MB-231Homo sapiens> 50000.0 nMNPASS
NON-PROTEIN TARGET= 31000.0 nM|> 100000.0 nMNPASS
P2X purinoceptor 7Mus musculusQ9Z1M075480 nM|= 75480.0 nMBindingDB, NPASS
PC-3Homo sapiens> 100000.0 nMNPASS
SASHomo sapiens> 100000.0 nMNPASS
SK-BR-3Homo sapiens> 50000.0 nMNPASS
SK-MEL-28Homo sapiens> 100000.0 nMNPASS
Trypanosoma cruziTrypanosoma cruzi> 2500000.0 nM|> 100000.0 nM|= 89050.0 nMNPASS
MCF7Homo sapiens> 50000.0 nMNPASS
RhodesainTrypanosoma brucei rhodesienseQ95PM0> 100000.0 nM|= 33000.0 nMNPASS
LoVoHomo sapiens> 100000.0 nMNPASS
Human immunodeficiency virus type 1 proteaseHuman immunodeficiency virus 1Q72874> 100000.0 nMNPASS
Indoleamine 2,3-dioxygenaseHomo sapiensP14902= 675000.0 nMNPASS
Human rhinovirus A proteaseHuman rhinovirus sp.Q4U254> 150000.0 nMNPASS
Human immunodeficiency virus type 1 integraseHuman immunodeficiency virus 1Q7ZJM1> 100000.0 nMNPASS
Histone-lysine N-methyltransferase SETD7Homo sapiensQ8WTS6>200000 nM|> 200000.0 nMBindingDB, NPASS
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEPHomo sapiensQ9Y2R2= 5600.0 nMNPASS
HeLaHomo sapiens> 100000.0 nM|= 71260.0 nMNPASS
HFF-1Homo sapiens> 50000.0 nMNPASS
Dihydroorotate dehydrogenase (quinone), mitochondrialSchistosoma mansoniG4VFD7= 29000.0 nMNPASS
Dihydroorotate dehydrogenase (quinone), mitochondrialSchistosoma mansoni29000 nMBindingDB
Cysteine proteaseTrypanosoma brucei rhodesiense33000 nM|>100000 nMBindingDB
A549Homo sapiens= 58000.0 nMNPASS
KBHomo sapiens= 105480.0 nMNPASS