IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

Bioactivity information

Target name	Target organism	UniProt identifier	EC50	IC50	Ki	Source
Dopamine D3 receptor	Homo sapiens	P35462		= 2.86 nM	= 0.971 nM	NPASS
Glycoprotein 42	Human herpesvirus 4 type 2	Q1HVG2		5640 nM		BindingDB
P-glycoprotein 1	Homo sapiens	P08183			= 24500.0 nM\|= 105200.0 nM	NPASS
P-glycoprotein 1	Mus musculus	P06795			= 19100.0 nM	NPASS
Rho-associated protein kinase 2	Homo sapiens	O75116		>59640 nM		BindingDB
Serotonin 1a (5-HT1a) receptor	Rattus norvegicus	P19327		= 3.107 nM	= 1.775 nM	NPASS
Serotonin 2b (5-HT2b) receptor	Homo sapiens	P41595		= 11.0 nM	= 6.855 nM	NPASS
Serotonin 2a (5-HT2a) receptor	Homo sapiens	P28223		= 28.0 nM	= 7.995 nM	NPASS
Dopamine D2 receptor	Homo sapiens	P14416		= 5.032 nM	= 1.677 nM	NPASS
Serotonin 2c (5-HT2c) receptor	Homo sapiens	P28335		= 104.0 nM	= 55.0 nM	NPASS
Serotonin 6 (5-HT6) receptor	Homo sapiens	P50406		= 15.0 nM	= 7.093 nM	NPASS
Thromboxane-A synthase	Homo sapiens	P24557		= 1993.0 nM		NPASS
Trypanosoma cruzi	Trypanosoma cruzi		= 18000.0 nM			NPASS
Serotonin 1b (5-HT1b) receptor	Rattus norvegicus	P28564		= 30.0 nM	= 19.0 nM	NPASS
Dopamine D1 receptor	Homo sapiens	P21728		= 294.0 nM	= 147.0 nM	NPASS
P-glycoprotein 3	Mus musculus	P21447			= 271500.0 nM	NPASS
D(1A) dopamine receptor	Bos taurus	Q95136			36 nM	BindingDB
D(2) dopamine receptor	Bos taurus	P20288			0.7 nM	BindingDB
5-hydroxytryptamine receptor 1A	Homo sapiens	P08908	18.02 nM			BindingDB
5-hydroxytryptamine receptor 7	Rattus norvegicus	P32305			14 nM\|8 nM	BindingDB
ATP-dependent translocase ABCB1	Homo sapiens	P08183			105200 nM\|24500 nM	BindingDB
ATP-dependent translocase ABCB1	Mus musculus	P06795			19100 nM	BindingDB
ATP-dependent translocase ABCB1	Mus musculus	P21447			271500 nM	BindingDB
Alpha-1a adrenergic receptor	Rattus norvegicus	P43140		= 11.0 nM	= 4.472 nM	NPASS
Alpha-1A adrenergic receptor	Rattus norvegicus	P43140			11 nM\|10 nM	BindingDB
Alpha-1d adrenergic receptor	Homo sapiens	P25100		= 18.0 nM	= 8.747 nM	NPASS
Alpha-2a adrenergic receptor	Homo sapiens	P08913		= 6.296 nM	= 2.361 nM	NPASS
Alpha-2b adrenergic receptor	Homo sapiens	P18089		= 3.058 nM	= 1.396 nM	NPASS
Alpha-2c adrenergic receptor	Homo sapiens	P18825		= 17.0 nM	= 2.409 nM	NPASS
Bcl-2-related protein A1	Mus musculus	Q07440		>100000 nM\|> 100000.0 nM		BindingDB, NPASS
Cytochrome P450 3A4	Homo sapiens	P08684		= 500.0 nM		NPASS
Alpha-1b adrenergic receptor	Rattus norvegicus	P15823		= 5.19 nM	= 2.873 nM	NPASS

a curated database

IMPPAT Phytochemical information:
Ergocornine

Bioactivity information

IMPPAT Phytochemical information: Ergocornine

Bioactivity information

IMPPAT Phytochemical information:
Ergocornine