IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

IMPPAT Phytochemical information:
Lobeline

Lobeline

Bioactivity information

Target name	Target organism	UniProt identifier	EC50	IC50	Kd	Ki	Source
SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2			> 20000.0 nM\|> 19952.62 nM			NPASS
Synaptic vesicular amine transporter	Rattus norvegicus	Q01827				4 nM\|6260 nM\|2760 nM\|470 nM\|= 2760.0 nM\|= 4.0 nM\|= 6260.0 nM\|= 470.0 nM	BindingDB, NPASS
Synaptic vesicular amine transporter	Mus musculus	Q8BRU6		381 nM\|= 381.0 nM			BindingDB, NPASS
Synaptic vesicular amine transporter	Homo sapiens	Q05940		4200 nM\|= 4200.0 nM		1840 nM\|>10000 nM\|1950 nM\|= 1840.0 nM\|> 10000.0 nM\|= 1950.0 nM	BindingDB, NPASS
Soluble acetylcholine receptor	Aplysia californica	Q8WSF8				= 2.512 nM	NPASS
Soluble acetylcholine receptor	Aplysia californica					2.51 nM	BindingDB
Serotonin 2a (5-HT2a) receptor	Homo sapiens	P28223				= 7400.0 nM	NPASS
Neuronal acetylcholine receptor; alpha4/beta2	Rattus norvegicus	P12390				= 40.0 nM	NPASS
Acetylcholine-binding protein	Lymnaea stagnalis	P58154				630.96 nM\|= 630.96 nM	BindingDB, NPASS
Neuronal acetylcholine receptor subunit alpha-7	Rattus norvegicus	Q05941				6260 nM	BindingDB
Neuronal acetylcholine receptor subunit alpha-7	Homo sapiens	P36544				7943.28 nM	BindingDB
Neuronal acetylcholine receptor subunit alpha-4/beta-2	Homo sapiens	P17787\|P43681				5.01 nM	BindingDB
Neuronal acetylcholine receptor protein alpha-7 subunit	Rattus norvegicus	Q05941				= 6260.0 nM	NPASS
Neuronal acetylcholine receptor protein alpha-7 subunit	Homo sapiens	P36544				= 7943.28 nM	NPASS
Neuronal acetylcholine receptor	Rattus norvegicus	Q05941		= 87.0 nM\|= 18100.0 nM		= 4.0 nM	NPASS
5-hydroxytryptamine receptor 2A	Homo sapiens	P28223				7400 nM	BindingDB
Neuronal acetylcholine receptor; alpha4/beta2	Homo sapiens	P43681				= 5.012 nM	NPASS