IMPPAT Phytochemical information: 
Noscapine
Noscapine
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
NON-PROTEIN TARGET> 2000.0 nM|> 1000.0 nM|= 80300.0 nM|= 34700.0 nM|= 20000.0 nM|= 70000.0 nMNPASS
U-251Homo sapiens= 40000.0 nMNPASS
Tubulin beta-3 chainHomo sapiensQ13509579 nMBindingDB
TubulinHomo sapiensQ9BUF5> 50000.0 nM= 144000.0 nM|= 1860.0 nMNPASS
TubulinBos taurusQ862F3> 400000.0 nM|= 170000.0 nMNPASS
Solute carrier family 22 member 2Homo sapiensO152442600 nM|= 2600.0 nMBindingDB, NPASS
Similar to alpha-tubulin isoform 1Bos taurus>400000 nM|170000 nMBindingDB
SNU-449Homo sapiens> 1000.0 nMNPASS
SNU-423Homo sapiens> 1000.0 nMNPASS
SNU-398Homo sapiens> 2000.0 nM|> 1000.0 nMNPASS
SNU-387Homo sapiens> 1000.0 nMNPASS
SMMC-7721Homo sapiens> 1000.0 nMNPASS
NCI/ADR-RESHomo sapiens= 17400.0 nMNPASS
SNU-475Homo sapiens> 1000.0 nMNPASS
Multidrug and toxin extrusion protein 1Homo sapiensQ96FL834500 nM|= 34500.0 nMBindingDB, NPASS
A549Homo sapiens= 25000.0 nM= 62900.0 nM|= 72900.0 nMNPASS
Bel-7402Homo sapiens> 1000.0 nMNPASS
CEMHomo sapiens= 14500.0 nMNPASS
Cytochrome P450 2C19Homo sapiensP33261= 400.3 nMNPASS
Cytochrome P450 2C9Homo sapiensP11712= 8177.3 nMNPASS
NB-4Homo sapiens> 20000.0 nMNPASS
HeLaHomo sapiens= 18400.0 nM= 24000.0 nM|= 25000.0 nMNPASS
Huh-7Homo sapiens> 1000.0 nMNPASS
JeKo-1Homo sapiens> 20000.0 nMNPASS
MCF7Homo sapiens= 42300.0 nM|= 57000.0 nM|= 18800.0 nM|= 42000.0 nMNPASS
MDA-MB-231Homo sapiens= 64000.0 nMNPASS
MOLM-13Homo sapiens> 20000.0 nMNPASS
HepG2Homo sapiens> 1000.0 nMNPASS