IMPPAT Phytochemical information: 
Rottlerin
Rottlerin
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
MIA PaCa-2Homo sapiens= 8000.0 nMNPASS
Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48Homo sapiens= 8000.0 nMNPASS
Serine/threonine-protein kinase EEF2KHomo sapiensO00418= 5300.0 nMNPASS
RuvB-like 1Homo sapiensQ9Y265= 10000.0 nMNPASS
Protein kinase C deltaHomo sapiensQ05655= 3000.0 nMNPASS
Plasmodium falciparumPlasmodium falciparum= 3981.07 nM|= 3162.28 nM|= 10000.0 nM|= 5011.87 nMNPASS
PC-3Homo sapiens> 20000.0 nMNPASS
Malate dehydrogenaseThermus thermophilusP10584= 700.0 nMNPASS
MAP kinase-activated protein kinase 5Homo sapiensQ8IW41= 1900.0 nMNPASS
Beta-lactamase AmpCEscherichia coli K-12P00811= 1200.0 nM|= 1800.0 nM|= 21000.0 nM|= 76000.0 nMNPASS
Lyssavirus rabiesLyssavirus rabies= 1000.0 nMNPASS
Huh-7Homo sapiens= 570.0 nMNPASS
HepG2Homo sapiens> 20000.0 nMNPASS
Hep 3B2Homo sapiens= 250.0 nMNPASS
HL-60Homo sapiens= 9000.0 nMNPASS
COLO 205Homo sapiens> 20000.0 nMNPASS
Beta-lactamaseEnterobacter cloacaeP05364= 96000.0 nM|= 142000.0 nMNPASS
Beta-chymotrypsinHomo sapiensP17538= 25000.0 nMNPASS
MAP kinase-activated protein kinase 2Homo sapiensP49137= 5400.0 nMNPASS