IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

Bioactivity information

Target name	Target organism	UniProt identifier	EC50	IC50	Source
U2OS	Homo sapiens			= 9490.0 nM	NPASS
MOLM-13	Homo sapiens			= 1838.0 nM\|= 934.5 nM	NPASS
MOLT-4	Homo sapiens			= 1700.0 nM	NPASS
MRC5	Homo sapiens			= 35040.0 nM\|= 37000.0 nM	NPASS
MV4-11	Homo sapiens			= 1439.0 nM\|= 289.1 nM	NPASS
NON-PROTEIN TARGET			= 11500.0 nM	= 5860.0 nM\|= 69460.0 nM\|= 2000.0 nM\|= 3200.0 nM\|= 4040.0 nM\|= 3430.0 nM\|= 3810.0 nM\|= 3900.0 nM	NPASS
NSCLC	Homo sapiens			= 9200.0 nM	NPASS
OCI-AML-3	Homo sapiens			= 1868.0 nM\|= 1109.0 nM	NPASS
Oryctolagus cuniculus	Oryctolagus cuniculus			= 20751000.0 nM\|= 6710000.0 nM	NPASS
P388	Mus musculus			= 2800.0 nM	NPASS
PC-3	Homo sapiens			= 4900.0 nM	NPASS
RAW264.7	Mus musculus			= 3000.0 nM	NPASS
SAOS-2	Homo sapiens			= 7310.0 nM	NPASS
SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2			> 50100.0 nM\|> 50118.72 nM	NPASS
SH-SY5Y	Homo sapiens			= 5940.0 nM	NPASS
SK-HEP1	Homo sapiens			= 13300.0 nM	NPASS
SK-MEL-2	Homo sapiens		= 4390.0 nM		NPASS
SW-620	Homo sapiens			= 4620.0 nM	NPASS
Signal transducer and activator of transcription 3	Homo sapiens	P40763		7000 nM\|= 7000.0 nM	BindingDB, NPASS
Staphylococcus aureus	Staphylococcus aureus			= 315330.0 nM	NPASS
T98G	Homo sapiens			= 4920.0 nM	NPASS
Thioredoxin reductase 1	Homo sapiens	Q16881		= 45880.0 nM\|= 1800.0 nM	NPASS
Thioredoxin reductase 1, cytoplasmic	Homo sapiens	Q16881		45880 nM\|1800 nM	BindingDB
Trypanosoma cruzi	Trypanosoma cruzi			= 21000.0 nM	NPASS
U-87 MG	Homo sapiens			= 16150.0 nM\|= 17340.0 nM\|= 7180.0 nM	NPASS
U-937	Homo sapiens			= 2174.0 nM\|= 767.0 nM\|= 1671.0 nM	NPASS
MKN-45	Homo sapiens			= 20000.0 nM	NPASS
WI-38	Homo sapiens		= 20300.0 nM\|= 8000.0 nM	= 26780.0 nM\|> 100000.0 nM\|= 8000.0 nM\|= 20300.0 nM	NPASS
MGC-803	Homo sapiens			= 2285.0 nM	NPASS
MCF7	Homo sapiens			= 6140.0 nM\|= 1200.0 nM\|= 8000.0 nM\|= 4400.0 nM\|= 9531.0 nM\|= 25000.0 nM	NPASS
20S proteasome	Homo sapiens	P49721\|P20618\|P28074\|P28062\|P28065\|P28072\|P25786\|P25787\|P25788\|P25789\|P28066\|P60900\|O14818\|Q8TAA3\|P40306\|A5LHX3\|P49720\|P28070\|Q99436		= 15000.0 nM	NPASS
8-MG-BA	Homo sapiens			= 10000.0 nM	NPASS
A-375	Homo sapiens		= 6170.0 nM	= 2500.0 nM	NPASS
A549	Homo sapiens		= 12200.0 nM	= 22850.0 nM\|= 6540.0 nM\|= 10000.0 nM\|= 6840.0 nM\|= 15220.0 nM\|= 15280.0 nM\|= 3200.0 nM\|= 10170.0 nM\|= 4998.0 nM	NPASS
AGS	Homo sapiens			= 20000.0 nM	NPASS
Aldose reductase	Homo sapiens	P15121		= 160000.0 nM	NPASS
Bel-7402	Homo sapiens			= 5600.0 nM	NPASS
Bel7402/5-FU	Homo sapiens			= 8400.0 nM	NPASS
CCRF-CEM	Homo sapiens			= 4400.0 nM	NPASS
CMK	Homo sapiens			= 2815.0 nM\|= 1911.0 nM\|= 612.7 nM\|= 421.8 nM	NPASS
Candida albicans	Candida albicans			= 94600.0 nM	NPASS
MDA-MB-231	Homo sapiens			= 8460.0 nM\|= 10600.0 nM\|= 3720.0 nM\|= 1720.0 nM	NPASS
DU-145	Homo sapiens			= 3400.0 nM	NPASS
Candida parapsilosis	Candida parapsilosis			= 94600.0 nM	NPASS
HCT-116	Homo sapiens			= 6040.0 nM\|= 9200.0 nM\|= 7340.0 nM\|= 8170.0 nM\|= 8130.0 nM\|= 6900.0 nM\|= 6380.0 nM\|= 13900.0 nM	NPASS
LN-229	Homo sapiens			= 10000.0 nM	NPASS
KB	Homo sapiens			= 1670.0 nM	NPASS
K562	Homo sapiens			= 5090.0 nM\|= 5050.0 nM\|= 5700.0 nM	NPASS
Forkhead box protein O3	Homo sapiens	O43524	= 37700.0 nM		NPASS
HepG2	Homo sapiens			= 8900.0 nM\|= 6800.0 nM\|= 8623.0 nM	NPASS
Jurkat	Homo sapiens			= 1400.0 nM\|= 5000.0 nM\|= 5300.0 nM	NPASS
HaCaT	Homo sapiens		= 4460.0 nM	= 16000.0 nM\|= 3030.0 nM	NPASS
HT-29	Homo sapiens			= 5490.0 nM\|= 2650.0 nM\|= 1400.0 nM	NPASS
HL-60	Homo sapiens			= 1778.0 nM\|= 2250.0 nM\|= 529.2 nM\|= 1128.0 nM\|= 5300.0 nM	NPASS
HGC-27	Homo sapiens			= 8100.0 nM\|= 760.0 nM\|= 8200.0 nM	NPASS
HCT-8	Homo sapiens			= 4100.0 nM\|= 2200.0 nM	NPASS
HeLa	Homo sapiens			= 16300.0 nM\|= 5148.0 nM	NPASS

a curated database

IMPPAT Phytochemical information:
Piperlongumine

Bioactivity information

IMPPAT Phytochemical information: Piperlongumine

Bioactivity information

IMPPAT Phytochemical information:
Piperlongumine