IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

Target name	Target organism	UniProt identifier	EC50	IC50	Ki	Source
A549	Homo sapiens			= 24590.0 nM		NPASS
SARS coronavirus 3C-like proteinase	SARS coronavirus	P0C6U8		= 21100.0 nM\|= 30000.0 nM\|= 60200.0 nM\|= 78900.0 nM	= 21500.0 nM	NPASS
Replicase polyprotein 1ab	Human SARS coronavirus	P0C6X7		21100 nM		BindingDB
Protease	Human immunodeficiency virus 1	Q9YQ12		= 147600.0 nM		NPASS
Papain	Carica papaya	P00784		88000 nM\|= 88000.0 nM		BindingDB, NPASS
NON-PROTEIN TARGET			= 17400.0 nM\|= 6600.0 nM\|= 27100.0 nM\|= 14800.0 nM			NPASS
MIA PaCa-2	Homo sapiens			= 22500.0 nM		NPASS
Liver carboxylesterase 1	Homo sapiens	P23141			2530 nM	BindingDB
Replicase polyprotein 1a	Severe acute respiratory syndrome coronavirus	P0C6U8		30000 nM\|78900 nM\|60200 nM\|21100 nM	21500 nM	BindingDB
HCT-116	Homo sapiens			= 12390.0 nM		NPASS
GABA-A receptor; anion channel	Bos taurus	P22300		= 300.0 nM		NPASS
Dual specificity phosphatase Cdc25A	Homo sapiens	P30304		> 20.0 ug.mL-1		NPASS
Cocaine esterase	Homo sapiens	O00748			84 nM\|40 nM	BindingDB
Carboxylesterase 2	Homo sapiens	O00748			= 83.7 nM\|= 40.0 nM	NPASS
Acyl coenzyme A:cholesterol acyltransferase	Homo sapiens	P23141			= 2530.0 nM	NPASS
Acetylcholinesterase	Homo sapiens	P22303			>100000 nM\|> 100000.0 nM	BindingDB, NPASS
HepG2	Homo sapiens		= 30900.0 nM\|= 12000.0 nM\|= 7100.0 nM			NPASS