IMPPAT Phytochemical information: 
1,4-Dihydroxyanthraquinone
1,4-Dihydroxyanthraquinone
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
TransthyretinHomo sapiensP02766>100000 nM|> 100000.0 nMBindingDB, NPASS
Thioredoxin reductase 2, mitochondrialRattus norvegicusQ9Z0J5>200000 nM|> 200000.0 nMBindingDB, NPASS
Thioredoxin reductase 1, cytoplasmicRattus norvegicusO89049>200000 nM|> 200000.0 nMBindingDB, NPASS
NON-PROTEIN TARGET> 10000.0 nMNPASS
Monoamine oxidase BHomo sapiensP27338= 110000.0 nMNPASS
Monoamine oxidase AHomo sapiensP21397= 65.0 nM= 39.0 nMNPASS
L02Homo sapiens> 200000.0 nMNPASS
HCT-116Homo sapiens> 30.0 ug.mL-1NPASS
DNA topoisomerase IIHomo sapiensQ02880> 200000.0 nMNPASS
DNA topoisomerase 2-alpha/2-betaHomo sapiensP11388|Q02880>200000 nMBindingDB
Casein kinase I isoform deltaHomo sapiensP48730>40000 nMBindingDB
A-431Homo sapiens> 30.0 ug.mL-1NPASS
B16Mus musculus> 30.0 ug.mL-1NPASS
Casein kinase I alphaHomo sapiensP48729> 40000.0 nMNPASS
Casein kinase I isoform gamma-1Homo sapiensQ9HCP0>40000 nMBindingDB
Casein kinase I gamma 1Homo sapiensQ9HCP0> 40000.0 nMNPASS
Casein kinase I isoform alphaHomo sapiensP48729>40000 nMBindingDB
Casein kinase I deltaHomo sapiensP48730> 40000.0 nMNPASS