IMPPAT Phytochemical information: 
4'-Demethyldeoxypodophyllotoxin
4'-Demethyldeoxypodophyllotoxin
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
TubulinHomo sapiensQ9BUF5= 2000.0 nMNPASS
SiHaHomo sapiens= 2070.0 nM|= 53300.0 nM|= 43000.0 nMNPASS
RPMI-8226Homo sapiens= 230.0 nMNPASS
PC-3Homo sapiens= 140.0 nMNPASS
NON-PROTEIN TARGET= 9810.0 nMNPASS
Mus musculusMus musculus= 0.00281 ug.mL-1NPASS
LiverRattus norvegicus= 33750.0 nMNPASS
HeLaHomo sapiens= 74.0 nM|= 7430.0 nM|= 43000.0 nM|= 53300.0 nMNPASS
KidneyRattus norvegicus= 22990.0 nMNPASS
KBHomo sapiens= 7.8 nMNPASS
HepG2Homo sapiens= 16530.0 nMNPASS
HL-60Homo sapiens= 110.0 nM|= 2960.0 nMNPASS
CCRF S-180Mus musculus= 30.0 nMNPASS
A549Homo sapiens= 800.0 nM|= 3750.0 nM|= 1800.0 nM|= 3900.0 nMNPASS
LNCaPHomo sapiens= 150.0 nMNPASS