IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

Bioactivity information

Target name	Target organism	UniProt identifier	EC50	IC50	Kd	Ki	Source
Estrogen receptor	Homo sapiens	P03372		>10000 nM			BindingDB
Sex hormone-binding globulin	Homo sapiens	P04278		14 nM	0.631000 nM		BindingDB
Estrogen receptor alpha	Homo sapiens	P03372		> 10000.0 nM			NPASS
Estrogen receptor beta	Homo sapiens	Q92731		>10000 nM\|> 10000.0 nM			BindingDB, NPASS
G-protein coupled bile acid receptor 1	Homo sapiens	Q8TDU6	18300 nM\|= 18300.0 nM				BindingDB, NPASS
Glucocorticoid receptor	Homo sapiens	P04150		= 3206.0 nM		= 1457.0 nM	NPASS
Lanosterol 14-alpha demethylase	Homo sapiens	Q16850		50000 nM			BindingDB
Multidrug resistance-associated protein 4	Homo sapiens	O15439		> 133000.0 nM			NPASS
Nuclear receptor subfamily 1 group I member 3	Mus musculus	O35627		30000 nM			BindingDB
Progesterone receptor	Bos taurus	Q690N0		= 1935.0 nM		= 252.0 nM	NPASS
Sigma non-opioid intracellular receptor 1	Homo sapiens	Q99720				1200 nM	BindingDB
Testis-specific androgen-binding protein	Homo sapiens	P04278		= 14.0 nM	= 0.631 nM		NPASS
Solute carrier organic anion transporter family member 1A1	Rattus norvegicus	P46720				5400 nM\|= 5400.0 nM	BindingDB, NPASS
Solute carrier organic anion transporter family member [3-691]	Zebrafish					3.00e+4 nM	BindingDB
Steroid 5-alpha-reductase	Rattus norvegicus	P31214		= 1900.0 nM			NPASS
UDP-glucuronosyltransferase 1-6	Human	P19224		>3.00e+5 nM			BindingDB
UDP-glucuronosyltransferase 1A1	Human	P22309		4.3e+4 nM			BindingDB
UDP-glucuronosyltransferase 2B10	Human	P36537		>3.00e+5 nM			BindingDB
UDP-glucuronosyltransferase 2B7	Human	P16662		1.65e+5 nM			BindingDB
Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens	Q13936		34 nM\|38 nM			BindingDB
Voltage-gated L-type calcium channel alpha-1C subunit	Homo sapiens	Q13936		= 34.0 nM\|= 38.4 nM			NPASS
Cytochrome P450 51	Homo sapiens	Q16850		= 50000.0 nM			NPASS
Sigma opioid receptor	Homo sapiens	Q99720				= 1200.0 nM	NPASS
Cytochrome P450 3A4	Homo sapiens	P08684		10000 nM\|45 nM\|= 10000.0 nM\|= 47.2 nM\|= 54.0 nM\|= 45.1 nM\|= 47.0 nM			BindingDB, NPASS
Corticosteroid-binding globulin	Homo sapiens	P08185				191 nM	BindingDB
Cytochrome P450 19A1	Homo sapiens	P11511				= 600.0 nM	NPASS
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	Homo sapiens	Q15125				>100000 nM	BindingDB
3-beta-hydroxysteroid-delta(8),delta(7)-isomerase	Homo sapiens	Q15125				> 100000.0 nM	NPASS
3-oxo-5-alpha-steroid 4-dehydrogenase 1/2	Rattus norvegicus	P24008\|P31214		1900 nM			BindingDB
ATP-binding cassette sub-family C member 2	Homo sapiens	Q92887		>133000 nM			BindingDB
ATP-binding cassette sub-family C member 3	Homo sapiens	O15438		>133000 nM			BindingDB
ATP-binding cassette sub-family C member 4	Homo sapiens	O15439		>133000 nM			BindingDB
Alpha-synuclein	Homo sapiens	P37840		96800 nM\|= 96800.0 nM			BindingDB, NPASS
Androgen Receptor	Homo sapiens	P10275	= 3.162 nM\|= 1.1 nM\|= 1.9 nM	= 3.9 nM\|= 2.7 nM\|= 30.0 nM\|= 4.571 nM\|= 4.17 nM\|= 4.27 nM	= 0.4 nM	= 29.0 nM	NPASS
Androgen Receptor	Mus musculus	P19091	= 1.995 nM				NPASS
Cytochrome P450 1B1	Homo sapiens	Q16678				411800 nM\|= 411800.0 nM	BindingDB, NPASS
Androgen receptor	Homo sapiens	P10275	1.1 nM\|3.16 nM\|1.9 nM	4.7 nM\|4.2 nM\|4.3 nM\|3.9 nM\|2.7 nM\|30 nM\|4.57 nM		3.2 nM\|29 nM	BindingDB
Androgen Receptor	Rattus norvegicus	P15207		= 3.2 nM\|= 3090.3 nM\|= 6.169 nM\|= 6.5 nM		= 4.9 nM\|= 1.4 nM\|= 1.413 nM\|= 4.112 nM\|= 4.3 nM	NPASS
Androgen receptor	Rattus norvegicus	P15207		3.20 nM\|3090.3 nM\|6.5 nM		4.9 nM\|1.4 nM\|4.3 nM	BindingDB
Corticosteroid binding globulin	Homo sapiens	P08185				= 190.55 nM	NPASS
Androgen receptor	Mus musculus	P19091	2 nM	11 nM			BindingDB
Cholinesterase	Homo sapiens	P06276		5.350e+4 nM			BindingDB
Canalicular multispecific organic anion transporter 2	Homo sapiens	O15438		> 133000.0 nM			NPASS
Constitutive androstane receptor	Mus musculus	O35627		= 30000.0 nM			NPASS
C-8 sterol isomerase ERG2	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P32352				7760 nM	BindingDB
C-8 sterol isomerase	Saccharomyces cerevisiae S288c	P32352				= 7760.0 nM	NPASS
Bile salt export pump	Homo sapiens	O95342		105000 nM\|= 105000.0 nM			BindingDB, NPASS
Aromatase	Homo sapiens	P11511				600 nM	BindingDB
Canalicular multispecific organic anion transporter 1	Homo sapiens	Q92887		> 133000.0 nM			NPASS

a curated database

IMPPAT Phytochemical information:
Testosterone

Bioactivity information

IMPPAT Phytochemical information: Testosterone

Bioactivity information

IMPPAT Phytochemical information:
Testosterone