IMPPAT Phytochemical information: 
Withaferin A
Withaferin A
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
VeroChlorocebus aethiops= 1300.0 nM|= 6600.0 nMNPASS
SW480Homo sapiens= 4900.0 nMNPASS
SF-268Homo sapiens< 400.0 nMNPASS
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2P0DTD1= 630.0 nM|= 540.0 nMNPASS
RPMI-8226Homo sapiens= 258.0 nM|= 1600.0 nMNPASS
PC-3MHomo sapiens= 410.0 nMNPASS
PC-3Homo sapiens= 410.0 nMNPASS
PANC-1Homo sapiens= 1240.0 nMNPASS
Nuclear factor NF-kappa-B complexHomo sapiensQ00653|P19838|Q04206= 47.0 nMNPASS
NCI-H460Homo sapiens< 400.0 nMNPASS
Multiple myeloma cancer stem cell= 649.7 nMNPASS
MM1.SHomo sapiens= 53.0 nMNPASS
MIA PaCa-2Homo sapiens= 2930.0 nMNPASS
MCF7Homo sapiens= 3600.0 nM|= 1300.0 nM|= 570.0 nMNPASS
LNCaPHomo sapiens= 870.0 nM= 870.0 nMNPASS
HeLaHomo sapiens= 3000.0 nM|= 6300.0 nMNPASS
HFFHomo sapiens> 6800.0 nM> 6800.0 nMNPASS
HEK-293THomo sapiens= 299.0 nMNPASS
HCT-116Homo sapiens= 3700.0 nMNPASS
Bromodomain-containing protein 4Homo sapiensO60885> 20000.0 nMNPASS
Bromodomain-containing protein 3Homo sapiensQ15059> 20000.0 nMNPASS
BXPC-3Homo sapiens= 2780.0 nMNPASS
ARPE-19Homo sapiens= 37.0 nMNPASS
ACHNHomo sapiens> 2000.0 nMNPASS
A549Homo sapiens= 6600.0 nM|= 10100.0 nMNPASS
A2780Homo sapiens= 32.7 nMNPASS