IMPPAT Phytochemical information: 
Withanolide E
Withanolide E
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
ACHNHomo sapiens= 489.0 nM|= 460.0 nMNPASS
Bromodomain-containing protein 3Homo sapiensQ15059= 720.3 nM|= 2949.0 nMNPASS
Bromodomain-containing protein 4Homo sapiensO60885= 1523.0 nM|= 556.2 nMNPASS
CWR22RHomo sapiens= 70.0 nMNPASS
HFFHomo sapiens> 10000.0 nM> 2000.0 nMNPASS
LNCaPHomo sapiens= 60.0 nM= 60.0 nMNPASS
M14Homo sapiens> 2000.0 nMNPASS
NF-kappa-B inhibitor alphaHomo sapiensP2596318000 nMBindingDB
NF-kappaB inhibitor alphaHomo sapiensP25963= 18000.0 nMNPASS
SK-MEL-28Homo sapiens> 2000.0 nMNPASS