IMPPAT Phytochemical information: 
(2R)-2-[(1S)-1-[(8R,9S,10R,13S,14R,17S)-14,17-dihydroxy-10,13-dimethyl-1-oxo-4,7,8,9,11,12,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-1-hydroxyethyl]-4,5-dimethyl-2,3-dihydropyran-6-one
(2R)-2-[(1S)-1-[(8R,9S,10R,13S,14R,17S)-14,17-dihydroxy-10,13-dimethyl-1-oxo-4,7,8,9,11,12,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-1-hydroxyethyl]-4,5-dimethyl-2,3-dihydropyran-6-one
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
SK-MEL-28Homo sapiens> 2000.0 nMNPASS
NF-kappa-B inhibitor alphaHomo sapiensP25963>50000 nMBindingDB
RAW264.7Mus musculus= 10900.0 nMNPASS
M14Homo sapiens> 2000.0 nMNPASS
NF-kappaB inhibitor alphaHomo sapiensP25963> 50000.0 nMNPASS
HFFHomo sapiens> 2000.0 nMNPASS
ACHNHomo sapiens> 2000.0 nMNPASS
LNCaPHomo sapiens= 130.0 nMNPASS
CWR22RHomo sapiens= 70.0 nMNPASS