IMPPAT Phytochemical information: 
brefeldin A
brefeldin A
Bioactivity information
Target nameTarget organismUniProt identifierEC50IC50KdKiSource
Nuclear receptor subfamily 0 group B member 1Homo sapiensP51843134.26 nM|= 134.26 nMBindingDB, NPASS
PANC-1Homo sapiens= 80.0 nMNPASS
MDA-MB-231Homo sapiens= 54.0 nMNPASS
Major prion proteinHomo sapiensP041563505 nMBindingDB
n.a.> 67602.0 nMNPASS
L02Homo sapiens< 0.4 nM|< 1.0 nM|= 100.0 nM|= 94.0 nMNPASS
Plasmodium falciparumPlasmodium falciparum= 1995.26 nM|= 3162.28 nMNPASS
Prion proteinHomo sapiensP04156= 3505.0 nMNPASS
SARS-CoV-2Severe acute respiratory syndrome coronavirus 2= 20.0 nMNPASS
Steroidogenic factor 1Homo sapiensQ13285>67602 nMBindingDB
dengue virus type 2dengue virus type 2= 54.6 nMNPASS
PC-3Homo sapiens= 68.0 nMNPASS
HepG2Homo sapiens= 350.0 nM|= 180.0 nM|= 80.0 nM|= 120.0 nMNPASS
Dengue virus 2Dengue virus 2= 54600.0 nMNPASS
HT-29Homo sapiens= 160.0 nMNPASS
HL-60Homo sapiens= 25.0 nMNPASS
ECa-109 cell lineHomo sapiens= 140.0 nMNPASS
Dengue virus type 4Dengue virus 4= 54600.0 nMNPASS
Dengue virus 3Dengue virus 3= 54600.0 nMNPASS
Dengue virus 1Dengue virus 1= 54600.0 nMNPASS
DU-145Homo sapiens= 160.0 nMNPASS
Bel7402/5-FUHomo sapiens= 820.0 nMNPASS
Bel-7402Homo sapiens= 24.0 nM|= 70.0 nM|= 170.0 nMNPASS
A549Homo sapiens= 56.0 nMNPASS
A-375Homo sapiens= 39.0 nMNPASS
HeLaHomo sapiens= 70.0 nM|= 44.0 nMNPASS