IMPPAT Phytochemical information: 
Ferulic acid
Ferulic acid
View 3D structure using JSmol
Summary

SMILES: COc1cc(/C=C/C(=O)O)ccc1O
InChI: InChI=1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+
InChIKey: KSEBMYQBYZTDHS-HWKANZROSA-N
DeepSMILES: COccc/C=C/C=O)O))))ccc6O
Scaffold Graph/Node/Bond level: c1ccccc1
Scaffold Graph/Node level: C1CCCCC1
Scaffold Graph level: C1CCCCC1
Functional groups: c/C=C/C(=O)O; cO; cOC
Chemical classification
ClassyFire Kingdom: Organic compounds
ClassyFire Superclass: Phenylpropanoids and polyketides
ClassyFire Class: Cinnamic acids and derivatives
ClassyFire Subclass: Hydroxycinnamic acids and derivatives
NP Classifier Biosynthetic pathway: Shikimates and Phenylpropanoids
NP Classifier Superclass: Phenylpropanoids (C6-C3)
NP Classifier Class: Cinnamic acids and derivatives
Synonymous chemical names:
4-hydroxy-3-methoxy cinamic, 4-hydroxy-3-methoxy-cinnamic-acid, 4-hydroxy-3-methoxycinnamic acid, ferulate, ferulic acid, ferulic acid, trans-, ferulic acid,trans-, ferulic-acid, trans-ferulate, trans-ferulic acid
External chemical identifiers:
CID:445858; ChEMBL:CHEMBL32749; ChEBI:17620; ZINC:ZINC000000058258; FDASRS:AVM951ZWST; SureChEMBL:SCHEMBL15673; MolPort-000-490-395
Chemical structure download
2D:2D MOL2D MOL22D SDF
3D:3D MOL3D MOL23D SDF3D PDB3D PDBQT
Ferulic acid
Physicochemical properties
Property name Tool Property value
Molecular weight (g/mol) RDKit 0
Log P RDKit 0
Topological polar surface area (Å2) RDKit
Number of hydrogen bond acceptors RDKit
Number of hydrogen bond donors RDKit
Number of carbon atoms RDKit
Number of heavy atoms RDKit
Number of heteroatoms RDKit
Number of nitrogen atoms RDKit
Number of sulfur atoms RDKit
Number of chiral carbon atoms RDKit
Stereochemical complexity RDKit 0
Number of sp hybridized carbon atoms RDKit
Number of sp2 hybridized carbon atoms RDKit
Number of sp3 hybridized carbon atoms RDKit
Shape complexity RDKit
Number of rotatable bonds RDKit
Number of aliphatic carbocycles RDKit
Number of aliphatic heterocycles RDKit
Number of aliphatic rings RDKit
Number of aromatic carbocycles RDKit
Number of aromatic heterocycles RDKit
Number of aromatic rings RDKit
Total number of rings RDKit
Number of saturated carbocycles RDKit
Number of saturated heterocycles RDKit
Number of saturated rings RDKit
Number of Smallest Set of Smallest Rings (SSSR) RDKit
Ferulic acid
Drug-likeness properties
Property nameToolProperty value
Number of Lipinski’s rule of 5 violations RDKit 0
Lipinski’s rule of 5 filter RDKit Passed
Number of Ghose filter violations RDKit 0
Ghose filter RDKit Passed
Veber filter RDKit Good
Pfizer 3/75 filter RDKit Bad
GSK 4/400 filter RDKit Good
Weighted quantitative estimate of drug-likeness (QEDw) score RDKit 0.7153
Ferulic acid
Chemical descriptors
Ferulic acid
Predicted human target proteins
Protein identifierHGNC symbolCombined score from STITCH database
ENSP00000215832MAPK1700
ENSP00000220764DECR1825
ENSP00000263025MAPK3700
ENSP00000263321TYR784
ENSP00000267163RB1700
ENSP00000270776PGD700
ENSP00000307786CYCS819
ENSP00000342007CYP1A2700
ENSP00000343838UGT1A10700
ENSP00000362525UGT1A7700
ENSP00000362549UGT1A8700
ENSP00000369050CYP1A1700
ENSP00000377192G6PD728
ENSP00000396308DHFR700
ENSP00000418532UGT1A3700
ENSP00000420174ERVFRD-1809
The human target proteins were predicted using STITCH, a database of Chemical-Protein interaction networks.
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