IMPPAT Phytochemical information: 
Cinnamic acid
Cinnamic acid
View 3D structure using JSmol
Summary

SMILES: OC(=O)/C=C/c1ccccc1
InChI: InChI=1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+
InChIKey: WBYWAXJHAXSJNI-VOTSOKGWSA-N
DeepSMILES: OC=O)/C=C/cccccc6
Scaffold Graph/Node/Bond level: c1ccccc1
Scaffold Graph/Node level: C1CCCCC1
Scaffold Graph level: C1CCCCC1
Functional groups: c/C=C/C(=O)O
Chemical classification
ClassyFire Kingdom: Organic compounds
ClassyFire Superclass: Phenylpropanoids and polyketides
ClassyFire Class: Cinnamic acids and derivatives
ClassyFire Subclass: Cinnamic acids
NP Classifier Biosynthetic pathway: Shikimates and Phenylpropanoids
NP Classifier Superclass: Phenylpropanoids (C6-C3)
NP Classifier Class: Cinnamic acids and derivatives
Synonymous chemical names:
(e)-cinnamic acid, cinnamic acid, cinnamic acid*, cinnamic-acid, t-cinnamic acid, trans cinnamic acid, trans-cinnamic, trans-cinnamic acid
External chemical identifiers:
CID:444539; ChEMBL:CHEMBL27246; ChEBI:35697; ZINC:ZINC000016051516; FDASRS:U14A832J8D; SureChEMBL:SCHEMBL1332; MolPort-000-881-745
Chemical structure download
2D:2D MOL2D MOL22D SDF
3D:3D MOL3D MOL23D SDF3D PDB3D PDBQT
Cinnamic acid
Physicochemical properties
Property name Tool Property value
Molecular weight (g/mol) RDKit 0
Log P RDKit 0
Topological polar surface area (Å2) RDKit
Number of hydrogen bond acceptors RDKit
Number of hydrogen bond donors RDKit
Number of carbon atoms RDKit
Number of heavy atoms RDKit
Number of heteroatoms RDKit
Number of nitrogen atoms RDKit
Number of sulfur atoms RDKit
Number of chiral carbon atoms RDKit
Stereochemical complexity RDKit 0
Number of sp hybridized carbon atoms RDKit
Number of sp2 hybridized carbon atoms RDKit
Number of sp3 hybridized carbon atoms RDKit
Shape complexity RDKit
Number of rotatable bonds RDKit
Number of aliphatic carbocycles RDKit
Number of aliphatic heterocycles RDKit
Number of aliphatic rings RDKit
Number of aromatic carbocycles RDKit
Number of aromatic heterocycles RDKit
Number of aromatic rings RDKit
Total number of rings RDKit
Number of saturated carbocycles RDKit
Number of saturated heterocycles RDKit
Number of saturated rings RDKit
Number of Smallest Set of Smallest Rings (SSSR) RDKit
Cinnamic acid
Drug-likeness properties
Property nameToolProperty value
Number of Lipinski’s rule of 5 violations RDKit 0
Lipinski’s rule of 5 filter RDKit Passed
Number of Ghose filter violations RDKit 2
Ghose filter RDKit Failed
Veber filter RDKit Good
Pfizer 3/75 filter RDKit Bad
GSK 4/400 filter RDKit Good
Weighted quantitative estimate of drug-likeness (QEDw) score RDKit 0.6489
Cinnamic acid
Chemical descriptors
Cinnamic acid
Predicted human target proteins
Protein identifierHGNC symbolCombined score from STITCH database
ENSP00000261208HAL762
ENSP00000263321TYR761
ENSP00000320709ADIPOQ800
ENSP00000343838UGT1A10700
ENSP00000362525UGT1A7700
ENSP00000362549UGT1A8700
ENSP00000383042KDM1A800
ENSP00000418532UGT1A3700
ENSP00000459789RCOR1800
The human target proteins were predicted using STITCH, a database of Chemical-Protein interaction networks.
700